Clomipramine HCl

Catalog No.S2541 Batch:S254102

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Technical Data

Formula

C19H23ClN2.HCl

Molecular Weight 351.31 CAS No. 17321-77-6
Solubility (25°C)* In vitro DMSO 70 mg/mL (199.25 mM)
Water 70 mg/mL (199.25 mM)
Ethanol 70 mg/mL (199.25 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Clomipramine HCl is a tricyclic antidepressant acting as a potent inhibitor of 5-HT reuptake with an IC50 value of 1.5 nM. Clomipramine hydrochloride is used in research on depression, anxiety, and obsessive-compulsive disorder (OCD).
Targets
5-HT [1]

Protocol (from reference)

Selleck's Clomipramine HCl has been cited by 2 publications

Lysosomal sequestration of weak base drugs, lysosomal biogenesis, and cell cycle alteration [ Biomed Pharmacother, 2022, 153:113328] PubMed: 35785701
Reversal of Infected Host Gene Expression Identifies Repurposed Drug Candidates for COVID-19 [ bioRxiv, 2020, 2020/9/20.4.7.30734] PubMed: 32511305

RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.