Cimetidine

Catalog No.S1845 Batch:S184501

Print

Technical Data

Formula

C10H16N6S

Molecular Weight 252.34 CAS No. 51481-61-9
Solubility (25°C)* In vitro DMSO 51 mg/mL (202.1 mM)
Ethanol 4 mg/mL (15.85 mM)
Water Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Cimetidine (SKF-92334), a histamine congener, competitively inhibits histamine binding to histamine H2 receptors.
Targets
Histamine H2 receptor [1]

Protocol (from reference)

Selleck's Cimetidine has been cited by 4 publications

Bacterial infection reinforces host metabolic flux from arginine to spermine for NLRP3 inflammasome evasion [ Cell Rep, 2021, 34(10):108832] PubMed: 33691113
Proton Pump Inhibitors Inhibit PHOSPHO1 Activity and Matrix Mineralisation In Vitro [ Calcif Tissue Int, 2021, 109(6):696-705] PubMed: 34213594
Proton pump inhibitors inhibit PHOSPHO1 activity and matrix mineralisation in vitro [ bioRxiv, 2021, 10.1101/2021.04.29.441931] PubMed: None
Histamine Receptor Antagonists, Loratadine and Azelastine, Sensitize P-gp-overexpressing Antimitotic Drug-resistant KBV20C Cells Through Different Molecular Mechanisms. [ Anticancer Res, 2019, 39(7):3767-3775] PubMed: 31262903

RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.

SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.