Notes: 1:Clickable 2:Unclickable _ L-Type VDCC ψ InsulinExocytosis RYR IQGAP GLP-1 Low High (FSK/IBMX) Plasma AC Intestinal GLP-1 Release Mixed Meal GLP-1(9-36)Inactive Renal Clearance BTC BTC PDX-1 PDX-1 NFAT PDX-1 FOXO1 FOXO1 β Cell Growth& Anti-apoptosis ATPAMP ATPAMP TCACycle Glycolysis Glucose Glucose K ATP Channel K V Channel GLUT2 PTB1 InsulinTranscript CREB pS IBS-2 Insulin Pyr GK IRS-2 Epac 1/2 Piccala Bim2 Epac2 Gα S G βγ ATP SUR1 SUR1 SUR1 SUR1 Ca 2+ Ca 2+ ER AKAP Ca 2+ Rap1 Rapid Inactivation(>80% of Pool) GLP-1(7-36)Active K ir6.2 K ir6.2 K ir6.2 K ir6.2 P {{ board.text }} {{ board.text }} {{ board.text }} {{ board.text }} {{ group.title }} {{ text.text }} {{ button.text }} {{ group.title }} {{ text.text }}