HDAC10-IN-1

Catalog No.E1194 Synonyms: 10c

For research use only.

HDAC10-IN-1 (10c), a nanomolar inhibitors of HDAC10 with high specificity, inhibits HDAC10 with high specificity over HDAC6 and with no significant impact on class I HDACs, with a IC50 of 20 nM on danio rerio HDAC10 (drHDAC10).

HDAC10-IN-1 Chemical Structure

CAS No.

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Biological Activity

Description HDAC10-IN-1 (10c), a nanomolar inhibitors of HDAC10 with high specificity, inhibits HDAC10 with high specificity over HDAC6 and with no significant impact on class I HDACs, with a IC50 of 20 nM on danio rerio HDAC10 (drHDAC10).

Protocol (from reference)

Chemical Information

Molecular Weight 313.39
Formula

C18H23N3O2

CAS No.
Storage 3 years -20°C powder
2 years -80°C in solvent

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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