Guanosine

Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond.

Guanosine Chemical Structure

Guanosine Chemical Structure

CAS: 118-00-3

Selleck's Guanosine has been cited by 4 publications

Purity & Quality Control

Batch: Purity: 99.83%
99.83

Guanosine Related Products

Choose Selective Nucleoside Analog/Antimetabolite Inhibitors

Biological Activity

Description Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond.
In vitro
In vitro Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine can be phosphorylated to become guanosine monophosphate (GMP), cyclic guanosine monophosphate (cGMP), guanosine diphosp
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05711719 Recruiting
Metabolic Syndrome|Coronary Microvascular Dysfunction
Johns Hopkins University|Merck Sharp & Dohme LLC
June 16 2023 Phase 2
NCT05009901 Recruiting
Obstructive Sleep Apnea of Adult
University of British Columbia
June 1 2022 Phase 2|Phase 3
NCT04764669 Completed
Lewy Body Disease|Parkinson Disease
Eisai Inc.
February 25 2021 Phase 2
NCT04672954 Completed
Healthy
Boehringer Ingelheim
January 7 2021 Phase 1

Chemical Information & Solubility

Molecular Weight 283.24 Formula

C10H13N5O5

CAS No. 118-00-3 SDF Download Guanosine SDF
Smiles C1=NC2=C(N1C3C(C(C(O3)CO)O)O)N=C(NC2=O)N
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 56 mg/mL ( (197.71 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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