Troxipide

Catalog No.S4128 Batch:S412801

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Technical Data

Formula

C15H22N2O4

Molecular Weight 294.35 CAS No. 30751-05-4
Solubility (25°C)* In vitro DMSO 18 mg/mL (61.15 mM)
Ethanol 3 mg/mL (10.19 mM)
Water Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

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Biological Activity

Description Troxipide(KU 54) is a novel systemic non-antisecretory gastric cytoprotective agent with anti-ulcer, anti-inflammatory and mucus secreting properties irrespective of pH of stomach or duodenum.
In vitro

Troxipide is a novel antiulcer compound which has inhibitory effects on human neutrophil migration and activation induced by various stimulants.[1] Troxipide is a new gastric cytoprotective agent, which neither inhibits acid secretion nor has acid neutralizing activity, but has been clinically proven to heal gastritis and gastric ulcers. Troxipide is shown to inhibit neutrophil mediated inflammation and oxidative stress in addition to improving the gastric mucus composition and output. Furthermore, it is found to increase the secretion of cytoprotective prostaglandins. The gastric mucosal metabolism and blood flow are also enhanced by Troxipide. [2]

Protocol (from reference)

Selleck's Troxipide has been cited by 1 publication

3D imaging analysis on an organoid-based platform guides personalized treatment in pancreatic ductal adenocarcinoma [ J Clin Invest, 2022, 132(24)e151604] PubMed: 36282600

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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.