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How to Cite 1. For In-Text Citation (Materials & Methods): 2. For Key Resources Table: |
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Technical Data
| Formula | C19H22ClN5O.HCl |
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| Molecular Weight | 408.32 | CAS No. | 25332-39-2 | ||||
| Solubility (25°C)* | In vitro | DMSO | 4 mg/mL (9.79 mM) | ||||
| Water | Insoluble | ||||||
| Ethanol | Insoluble | ||||||
| In vivo (Add solvents to the product individually and in order) |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Trazodone HCl (AF-1161, KB-831) is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders. | |
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Protocol (from reference)
Selleck's Trazodone HCl Has Been Cited by 6 Publications
| Dose–Response Effects of 7-Dehydrocholesterol Reductase Inhibitors on Sterol Profiles and Vesicular Stomatitis Virus Replication [ ACS Pharmacology & Translational Science, October 25, 2022, 1086-1096] | PubMed: 36407960 |
| Investigating Psychopharmaceutical Effects on Early Vertebrate Development Using a Zebrafish Model System [ Journal of Developmental Biology, June 27, 2025, 22] | PubMed: 40700140 |
| Development of a CYP2D6-enhanced HepaRG cell model with improved CYP2D6 metabolic capacity [ PLOS ONE, 2025, e0339559] | PubMed: 41460788 |
| Chronic Aripiprazole and Trazodone Polypharmacy Effects on Systemic and Brain Cholesterol Biosynthesis [ Biomolecules, 2023, 1321] | PubMed: 37759721 |
| Individual and simultaneous treatment with antipsychotic aripiprazole and antidepressant trazodone inhibit sterol biosynthesis in the adult brain [ J Lipid Res, 2022, 63(8):100249] | PubMed: 35839864 |
| Dose–Response Effects of 7-Dehydrocholesterol Reductase Inhibitors on Sterol Profiles and Vesicular Stomatitis Virus Replication [ ACS Pharmacology & Translational Science, 2022, 1086-1096] | PubMed: 36407960 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.