SU0268

Catalog No.S9905 Batch:S990501

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Technical Data

Formula

C26H25N3O4S

Molecular Weight 475.56 CAS No. 2210228-45-6
Solubility (25°C)* In vitro DMSO 95 mg/mL (199.76 mM)
Ethanol 2 mg/mL (4.2 mM)
Water Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description SU0268 is a potent and specific inhibitor of 8-Oxoguanine DNA glycosylase 1 (OGG1), with the IC50 of 0.059 μM.
Targets
OGG1 [1]
(in the fluorogenic 8-OG excision assay)
0.059 μM

Protocol (from reference)

Selleck's SU0268 has been cited by 1 publication

OGG1 Inhibition Triggers Synthetic Lethality and Enhances The Effect of PARP Inhibitor Olaparib in BRCA1-Deficient TNBC Cells [ Front Oncol, 2022, 12:888810] PubMed: 35619904

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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.