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Technical Data
| Formula | C10H26N4.4HCl |
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| Molecular Weight | 348.18 | CAS No. | 306-67-2 | |
| Solubility (25°C)* | In vitro | Water | 69 mg/mL (198.17 mM) | |
| DMSO | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Spermine (Gerontine, Neuridine, Musculamine) is a polyamine involved in cellular metabolism found in all eukaryotic cells. It is a major natural intracellular compound capable of protecting DNA from free radical attack. |
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Protocol (from reference)
Selleck's Spermine Tetrahydrochloride has been cited by 4 publications
| Metabolic support by macrophages sustains colonic epithelial homeostasis [ Cell Metab, 2023, S1550-4131(23)00341-8] | PubMed: 37804836 |
| Difluoromethylornithine Induces Apoptosis through Regulation of AP-1 Signaling via JNK Phosphorylation in Epithelial Ovarian Cancer [ Int J Mol Sci, 2021, 22(19)10255] | PubMed: 34638596 |
| Difluoromethylornithine Induces Apoptosis through Regulation of AP-1 Signaling via JNK Phosphorylation in Epithelial Ovarian Cancer [ Int J Mol Sci, 2021, 22(19), 10255] | PubMed: None |
| Melatonin fine-tunes intracellular calcium signals and eliminates myocardial damage through the IP3R/MCU pathways in cardiorenal syndrome type 3. [ Biochem Pharmacol, 2020, 174:113832] | PubMed: 32006470 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.