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Rat IgG2b isotype control-InVivo
Catalog No.A2116 Batch: A211617
Clone No.LTF-2
Rat IgG2b isotype control-InVivo monoclonal antibody (Clone:LTF-2) reacts with keyhole limpet hemocyanin (KLH). Because KLH is not expressed by mammals this antibody is ideal for use as an isotype-matched control for rat IgG2b antibodies in most in vivo and in vitro applications.
Technical Data
| Formulation | PBS Buffer, PH 7.4 |
|---|---|
| Clone | LTF-2 |
| Isotype | Rat IgG2b, κ |
| Source | CHO |
| Murine Pathogen Screening Panel | all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus. |
| Storage (From the date of receipt) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles |
| Sterility | 9.08 mg/ml |
| Purity | 99% |
| Protein concentration | 9.08 mg/ml |
| Endotoxin Level | ＜1EU/mg |
Customer Product Validation
Selleck's Rat IgG2b isotype control-InVivo Has Been Cited by 71 publications
| FLT3L combined with GM-CSF induced dendritic cells drive broad tumor-specific CD8+ T cell responses and remodel the tumor microenvironment to enhance anti-tumor efficacy [ Frontiers in Immunology, September 4, 2025, 16:1649891] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=40977690 |
| Urokinase-type plasminogen activator deficiency enhances CD8+ T cell infiltration and anti-PD-1 therapy efficacy in prostate cancer [ Frontiers in Immunology, September 1, 2025, 16:1625226] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=40959092 |
| Beta-1,4-galactosyltransferase-3 deficiency suppresses the growth of immunogenic tumors in mice [ Frontiers in Immunology, October 9, 2023, 14:1272537] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=37901252 |
| Oncolytic virus M1 functions as a bifunctional checkpoint inhibitor to enhance the antitumor activity of DC vaccine [ Cell Reports Medicine, October 1, 2023, 4(10):101229] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=37820722 |
| Silencing PCSK9 reshapes the spatiotemporal activation of STING for safe and effective cancer immunotherapy [ Nature Communications, November 25, 2025, 16(1):11622] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=41290746 |
| Low-dose radiotherapy combined with dual PD-L1 and VEGFA blockade elicits antitumor response in hepatocellular carcinoma mediated by activated intratumoral CD8+ exhausted-like T cells [ Nature Communications, November 24, 2023, 14(1):7709] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=38001101 |
| Tumor cell-specific loss of GPX4 reprograms triacylglycerol metabolism to escape ferroptosis and impair antitumor immunity in NSCLC [ bioRxiv, November 13, 2025, 2025.11.12.687999] | |
| Simvastatin overcomes the pPCK1-pLDHA-SPRINGlac axis-mediated ferroptosis and chemo-immunotherapy resistance in AKT-hyperactivated intrahepatic cholangiocarcinoma [ Cancer Communications, May 29, 2025, 45(8):1038-1071] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=40443016 |
| DOCK2 protects against bacterial sepsis by constraining T helper 1 response [ Frontiers in Immunology, May 29, 2025, 16:1527934] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=40510337 |
| Mannose-binding lectin 2 secreted by hepatocellular carcinoma cells recruits and activates natural killer cells to reshape an immune-activated microenvironment [ PLOS Biology, May 20, 2026, 24(5):e3003793] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=42160305 |
FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS.
Specific storage and handling information for each product is indicated on the product datasheet. Most Selleck products are stable under the recommended conditions. Products are sometimes shipped at a temperature that differs from the recommended storage temperature. Short-term storage of many products are stable in the short-term at temperatures that differ from that required for long-term storage.
We ensure that the product is shipped under conditions that will maintain the quality of the reagents. Upon receipt of the product, follow the storage recommendations on the product data sheet.