Rat IgG2a isotype control-InVivo

Catalog No.A2123 Batch: A212320

Clone No.2A3

Rat IgG2a isotype control-InVivo can be used as an isotype-matched control for rat IgG2a antibodies.

Technical Data

Formulation	PBS buffer (pH=7.4)
Clone	2A3
Isotype	Rat IgG2a, κ
Source	CHO
Murine Pathogen Screening Panel	all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus.
Storage (From the date of receipt)	Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Sterility	8.57 mg/ml
Purity	99%
Protein concentration	8.57 mg/ml
Endotoxin Level	＜1EU/mg

Selleck's Rat IgG2a isotype control-InVivo Has Been Cited by 40 publications

Nuclear glycine decarboxylase suppresses STAT1-dependent MHC-I and promotes cancer immune evasion [ The EMBO Journal, September 8, 2025, 44(20):5712-5733]	https://www.ncbi.nlm.nih.gov/pubmed/?term=40926122
Yin Yang 1 Promotes Antiprogrammed Cell Death-1 Resistance in Hepatocellular Carcinoma through Polypeptide N-Acetylgalactosaminyltransferase 16-Mediated Glycosylation of Programmed Death Ligand-1 [ MedComm, November 26, 2025, 6(12):e70504]	https://www.ncbi.nlm.nih.gov/pubmed/?term=41322030
Interleukin-21 receptor signaling promotes metabolic dysfunction-associated steatohepatitis-driven hepatocellular carcinoma by inducing immunosuppressive IgA+ B cells [ Molecular Cancer, May 8, 2024, 95]	https://www.ncbi.nlm.nih.gov/pubmed/?term=38720319
Oncolytic virus M1 reinvigorates CD8+ T-cell immunity against glioblastoma through B-cell-dependent antigen cross-presentation in the spleen [ Cellular and Molecular Immunology, March 4, 2026, 23(4):349-366]	https://www.ncbi.nlm.nih.gov/pubmed/?term=41781696
PD-1 blockade plus tyrosine kinase inhibitor remodels the tumor microenvironment in advanced renal cell carcinoma [ Nature Communications, March 31, 2026, 17(1):4626]	https://www.ncbi.nlm.nih.gov/pubmed/?term=41916996
PUS1 Drives Renal Cancer Progression by Preventing Formation of Endogenous Double-stranded RNAs [ International Journal of Biological Sciences, March 25, 2026, 22(7):3749-3768]	https://www.ncbi.nlm.nih.gov/pubmed/?term=42003926
PUS1 Drives Renal Cancer Progression by Preventing Formation of Endogenous Double-stranded RNAs [ International Journal of Biological Sciences, March 25 2026, 3749-3768]	https://www.ncbi.nlm.nih.gov/pubmed/?term=42003926
Spatial heterogeneity of MDSCs mediated by ANXA1-FPRs signaling drives immune suppression in OSCC progression [ Nature Communications, March 18, 2026, 17(1):2535]	https://www.ncbi.nlm.nih.gov/pubmed/?term=41851114
Spatial heterogeneity of MDSCs mediated by ANXA1-FPRs signaling drives immune suppression in OSCC progression [ Nature Communications, March 18 2026, 2535]	https://www.ncbi.nlm.nih.gov/pubmed/?term=41851114
Differential substrate degradation by super-degron: EGFP in wild-type mouse cells, PD-1 requires CRBN humanization [ iScience, June 23, 2025, 112992]	https://www.ncbi.nlm.nih.gov/pubmed/?term=40687785

FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS.

Specific storage and handling information for each product is indicated on the product datasheet. Most Selleck products are stable under the recommended conditions. Products are sometimes shipped at a temperature that differs from the recommended storage temperature. Short-term storage of many products are stable in the short-term at temperatures that differ from that required for long-term storage.
We ensure that the product is shipped under conditions that will maintain the quality of the reagents. Upon receipt of the product, follow the storage recommendations on the product data sheet.