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Technical Data
| CAS No. | 946415-13-0 |
|---|---|
| Formulation | PBS Buffer, PH 7.4 |
| Isotype | Human IgG1, κ |
| Application | Pamrevlumab (anti-CTGF) |
| Storage (From the date of receipt) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. |
| Purity | 99% |
| Protein concentration | 6.84 mg/ml |
| Endotoxin Level | ＜1EU/mg |
Biological Activity
| Description | Pamrevlumab, a recombinant human antibody that binds to connective tissue growth factor (CTGF) has emerged as a potential therapy for idiopathic pulmonary fibrosis (IPF). |
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| References |
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Customer Product Validation
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Selleck's Pamrevlumab (anti-CTGF) Has Been Cited by 5 publications
| Microvascular Endothelial Cells License APS Vasculopathy Through YAP1- and CCN2-Mediated Signaling [ Circulation, 2025, Online ahead of print] |
https://www.ncbi.nlm.nih.gov/pubmed/?term= |
| Targeting CTGF overcomes resistance to CSF1R inhibitors by preventing CAF activation in colorectal cancer [ Cell Reports Medicine, 2025, 102480] |
https://www.ncbi.nlm.nih.gov/pubmed/?term= |
| [ Cell Commun Signal, 2024, ] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=38291510 |
| ER stress-induced YAP upregulation leads to chondrocyte phenotype loss in age-related osteoarthritis [ Front Pharmacol, 2024, 15:1476255] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=39600372 |
| ER stress-induced YAP upregulation leads to chondrocyte phenotype loss in age-related osteoarthritis [ Frontiers in Pharmacology, 2024, 1476255] |
https://www.ncbi.nlm.nih.gov/pubmed/?term= |
FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS.
Specific storage and handling information for each product is indicated on the product datasheet. Most Selleck products are stable under the recommended conditions. Products are sometimes shipped at a temperature that differs from the recommended storage temperature. Short-term storage of many products are stable in the short-term at temperatures that differ from that required for long-term storage.
We ensure that the product is shipped under conditions that will maintain the quality of the reagents. Upon receipt of the product, follow the storage recommendations on the product data sheet.