OPRD1 Rabbit Recombinant mAb Datasheet

Description

Specificity	OPRD1 Rabbit Recombinant mAb detects endogenous level of total OPRD1.
Background	The opioid receptor family consists of three receptors, mu, delta, and kappa. Opioid receptors are broadly expressed throughout the peripheral and central nervous systems. They are seven-transmembrane proteins which belong to the G protein-coupled receptor (GPCR) superfamily. Upon binding of exogenous opiates or endogenous opioid peptides, opioid receptors are activated and convey extracellular stimulation to multiple intracellular effectors, including ion channels and second messengers that ultimately decrease neuronal activity. DOR (delta opioid receptor) activation can regulate drug reward, inhibitory controls and learning processes.

Specificity

OPRD1 Rabbit Recombinant mAb detects endogenous level of total OPRD1.

Background

The opioid receptor family consists of three receptors, mu, delta, and kappa. Opioid receptors are broadly expressed throughout the peripheral and central nervous systems. They are seven-transmembrane proteins which belong to the G protein-coupled receptor (GPCR) superfamily. Upon binding of exogenous opiates or endogenous opioid peptides, opioid receptors are activated and convey extracellular stimulation to multiple intracellular effectors, including ion channels and second messengers that ultimately decrease neuronal activity. DOR (delta opioid receptor) activation can regulate drug reward, inhibitory controls and learning processes.

Usage Information

Application

WB, IHC,ELISA

Dilution

WB	IHC
1:1000	1:50

Reactivity

Human Mouse Rat

MW (kDa)

40kDa

Source

Rabbit

Concentration

1mg/ml

Storage buffer

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

Storage
(From the date of receipt)

Store at –20°C.

References

Application Data

WB

Validated by Selleck

IHC