NSAH

Catalog No.S3385 Batch:S338501

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Technical Data

Formula

C18H14N2O3

Molecular Weight 306.32 CAS No. 1099592-35-4
Solubility (25°C)* In vitro DMSO 61 mg/mL (199.13 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description NSAH (HNASH) is a reversible and competitive nonnucleoside ribonucleotide reductase (RNR) inhibitor, with cell-free IC50 of 32 μM and cell-based IC50 of ~250 nM, respectively.
Targets
RNR [1]
(in RR inhibition assay (cell-based))
RNR [1]
(in RR inhibition assay (non-cell))
250 nM 32 μM

Protocol (from reference)

Selleck's NSAH has been cited by 1 publication

Efficient Induction of Antigen-Specific CD8+ T-Cell Responses by Cationic Peptide-Based mRNA Nanoparticles [ Pharmaceutics, 2022, 14-71387] PubMed: 35890284

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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.