NF-κB-IN-1

Catalog No.E0796 Batch:E079601

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Technical Data

Formula

C31H30O8

Molecular Weight 530.57 CAS No. 1227098-15-8
Solubility (25°C)* In vitro DMSO 50 mg/mL (94.23 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

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Biological Activity

Description NF-κB-IN-1 is a potent NF-κB signaling pathway inhibitor, which acts by directly inhibiting inhibitory κB kinase (IKK).
Targets
IKK [1] NF-κB [1]

Protocol (from reference)

Selleck's NF-κB-IN-1 has been cited by 2 publications

Advanced glycation end products regulate the receptor of AGEs epigenetically [ Front Cell Dev Biol, 2023, 11:1062229] PubMed: 36866277
CaM/CaMKII mediates activation and proliferation of hepatic stellate cells regulated by ASIC1a [ Front Pharmacol, 2022, 13:996667] PubMed: 36588718

RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.