Mouse IgG1 isotype control-InVivo

Catalog No.A2106 Batch: A210610

Clone No.MOPC-21

The monoclonal mouse IgG1 K immunoglobulin is ideal for use as a non-reactive isotype-matched control for mouse IgG1 antibodies in most in vivo and in vitro applications.

Technical Data

Formulation	PBS buffer, pH 7.0
Clone	MOPC-21
Isotype	mouse IgG1,κ
Application	Mouse IgG1 isotype control-InVivo FCM,IHC,IP,WB
Source	CHO
Murine Pathogen Screening Panel	all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus.
Storage (From the date of receipt)	Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Sterility	7.74 mg/ml
Purity	99%
Protein concentration	7.74 mg/ml
Endotoxin Level	＜1EU/mg

Selleck's Mouse IgG1 isotype control-InVivo Has Been Cited by 15 publications

Cardiac arrest triggers IL-17-mediated neuroinflammation and astrocyte polarization: insights into pathogenesis and intervention [ Journal of Neuroinflammation, November 14, 2025, 22(1):268]	https://www.ncbi.nlm.nih.gov/pubmed/?term=41239323
Genome-Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma [ Advanced Science, May 26, 2026, e15158]
Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma [ Advanced Science, May 26, 2026, e15158]	https://www.ncbi.nlm.nih.gov/pubmed/?term=42189126
ABHD17C‐Mediated S‐Depalmitoylation of BCL6B Enhances CD24 Transcription to Resist Macrophage Phagocytosis in Pancreatic Cancer [ Advanced Science, May 19, 2026, e75757]	https://www.ncbi.nlm.nih.gov/pubmed/?term=42154583
Fungal pathogen-responsive Th17 cells in gut-mouth axis enhance protection against oropharyngeal candidiasis [ iScience, June 1, 2025, 28(6):112675]	https://www.ncbi.nlm.nih.gov/pubmed/?term=40510134
Targeting IFN-I driven tertiary lymphoid structures halts B cell-mediated bone loss in periodontitis [ International Journal of Oral Science, July 27, 2026, 18(1):53]	https://www.ncbi.nlm.nih.gov/pubmed/?term=42503518
Type I IFN Dynamics Define an Early Checkpoint for Survival and Orchestrate Systemic Neutrophil Heterogeneity in Lethal Viral Infection [ nan, January 24, 2026, nan]
CircMVP promotes METTL3 activation mediated CTNNB1 m6A modification in the inhibition of colorectal cancer in B7-H3 dependence antitumor immunity [ International Journal of Biological Sciences, January 1, 2025, 21(1):306-327]	https://www.ncbi.nlm.nih.gov/pubmed/?term=39744434
Disruption of FGL2 induces TFEB-dependent lysosomal degradation of PD-L1 and enhances the efficacy of anti-PD1 therapy in hepatocellular carcinoma [ Cell Communication and Signaling, February 2, 2026, 155]	https://www.ncbi.nlm.nih.gov/pubmed/?term=41629991
Targeting immune cells in the aged brain reveals that engineered cytokine IL-10 enhances neurogenesis and improves cognition [ Immunity, February 1, 2026, 59(2):458-476.e13]	https://www.ncbi.nlm.nih.gov/pubmed/?term=41619730

FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS.

Specific storage and handling information for each product is indicated on the product datasheet. Most Selleck products are stable under the recommended conditions. Products are sometimes shipped at a temperature that differs from the recommended storage temperature. Short-term storage of many products are stable in the short-term at temperatures that differ from that required for long-term storage.
We ensure that the product is shipped under conditions that will maintain the quality of the reagents. Upon receipt of the product, follow the storage recommendations on the product data sheet.