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Technical Data
| Formula | C15H14O4 |
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| Molecular Weight | 258.27 | CAS No. | 3562-99-0 | |
| Solubility (25°C)* | In vitro | DMSO | 51 mg/mL (197.46 mM) | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Menbutone (Genabilin, Naftobil, Genabilic acid), or genabilic acid, is a derivative of oxybutyric acid which acts as a choleretic stimulating secretion, a trypsinogen and a pepsinogen. |
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| In vivo | Acute toxicity of menbutone in rabbits occurrs at accidental high doses, as the lethal dose is about 50 fold over the recommended therapeutic dose for other animals. Cardiac muscle, liver and kidneys are the main target organs for menbutone toxicity. Menbutone is not recommended for use in rabbits suffering from any cardiac and hepatic disorders, especially in overdosing situations. The calculated LD50 is 475 mg/kg BW in rabbits, indicating that menbutone has a relatively wide safety margin[1]. |
Protocol (from reference)
| Animal Study:[1] |
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RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.