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Technical Data
| CAS No. | 2169232-81-7 |
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| Formulation | PBS Buffer, PH 7.4 |
| Isotype | Human IgG4 |
| Application | Magrolimab (anti-CD47) |
| Source | CHO cells |
| Storage (From the date of receipt) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. |
Biological Activity
| Description | Magrolimab (anti-CD47) (5F9, GS-4721,Hu5F9 G4,ONO 7913) is a first-in-class macrophage immune checkpoint inhibitor that mainly binds to N-terminal pyroglutamate of CD47. |
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Customer Product Validation
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Selleck's Magrolimab (anti-CD47) has been cited by 2 publications
| The "don't eat me" signal CD47 is associated with microglial phagocytosis defects and autism-like behaviors in 16p11.2 deletion mice [ Proc Natl Acad Sci U S A, 2025, 122(16):e2411080122] | PubMed: 40238451 |
| Maplirpacept: a CD47 decoy receptor with minimal red blood cell binding and robust anti-tumor efficacy [ Front Immunol, 2025, 16:1518787] | PubMed: 40078999 |
FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS.
Specific storage and handling information for each product is indicated on the product datasheet. Most Selleck products are stable under the recommended conditions. Products are sometimes shipped at a temperature that differs from the recommended storage temperature. Short-term storage of many products are stable in the short-term at temperatures that differ from that required for long-term storage.
We ensure that the product is shipped under conditions that will maintain the quality of the reagents. Upon receipt of the product, follow the storage recommendations on the product data sheet.