KLF4 Rabbit Recombinant mAb Datasheet

Description

Specificity	KLF4 Rabbit Recombinant mAb detects endogenous level of total KLF4.
Background	The Krüppel-like factor 4 (KLF4) is a zinc-finger transcription factor that plays a critical role in embryonic development, stemness and cancer, where it can act either as oncogene or tumor suppressor. It is enriched primarily in post-mitotic, terminally differentiated epithelial cells in the skin and intestine. KLF4 is one of the four factors required for reprogramming of adult fibroblasts and skin melanocytes into induced pluripotent stem cells.

Specificity

KLF4 Rabbit Recombinant mAb detects endogenous level of total KLF4.

Background

The Krüppel-like factor 4 (KLF4) is a zinc-finger transcription factor that plays a critical role in embryonic development, stemness and cancer, where it can act either as oncogene or tumor suppressor. It is enriched primarily in post-mitotic, terminally differentiated epithelial cells in the skin and intestine. KLF4 is one of the four factors required for reprogramming of adult fibroblasts and skin melanocytes into induced pluripotent stem cells.

Usage Information

Application

WB, IF,ELISA

Dilution

WB	IF
1:1000	1:50

Reactivity

Human Mouse Rat

MW (kDa)

54kDa

Source

Rabbit

Concentration

1mg/ml

Storage buffer

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

Storage
(From the date of receipt)

Store at –20°C.

References

[1] M Riverso, et al. Oncogene. 2017: 36, 3322-3333.

Application Data

WB

Validated by Selleck

IF