GW7647

Catalog No.S8046 Batch:S804601

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Technical Data

Formula

C29H46N2O3S

Molecular Weight 502.75 CAS No. 265129-71-3
Solubility (25°C)* In vitro DMSO 100 mg/mL (198.9 mM)
Ethanol 25 mg/mL (49.72 mM)
Water Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description GW7647 is a potent PPARα agonist, with EC50s of 6 nM, 1.1 μM, and 6.2 μM for human PPARα, PPARγ and PPARδ, respectively.
Targets
human PPARα [1]
(in an established cell-based reporter assay)
human PPARγ [1]
(in an established cell-based reporter assay)
human PPARδ [1]
(in an established cell-based reporter assay)
6 nM(EC50) 1.1 μM(EC50) 6.2 μM(EC50)
In vitro

GW7647 activates human PPARα, PPARγ, and PPARδ with EC50 of 0.006, 1.1 and 6.2 µM, respectively, in a GAL4-PPAR binding assay. Similar EC50 of 0.001, 1.3, and 2.9 are observed with the murine receptors. [1]

Protocol (from reference)

RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.