GSK2643943A

Catalog No.S6878 Batch:S687803

Print

Technical Data

Formula

C17H12FN3

Molecular Weight 277.30 CAS No. 2449301-27-1
Solubility (25°C)* In vitro DMSO 55 mg/mL (198.34 mM)
Ethanol 6 mg/mL (21.63 mM)
Water Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description GSK2643943A is an inhibitor of deubiquitylating enzyme (DUB) with IC50 of 160 nM for USP20/Ub-Rho.
Targets
USP20/Ub-Rho [1]
(Cell-free assay)
160 nM

Protocol (from reference)

Selleck's GSK2643943A has been cited by 1 publication

Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis [ Nature, 2020, 10.1038/s41586-020-2928-y] PubMed: 33177714

RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.

SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.