Glycogen synthase Rabbit Recombinant mAb

Catalog No.A5358

Description

Specificity	Glycogen synthase Rabbit Recombinant mAb detects endogenous level of total glycogen synthase.
Background	Glycogen synthase (GS), a key enzyme in glycogen synthesis, is activated by the allosteric stimulator glucose-6-phosphate (G6P) and by dephosphorylation through inactivation of GS kinase-3 with insulin. It is a glycosyltransferase that catalyzes the conversion of the glucosyl (Glc) moiety of uridine diphosphate glucose (UDP-Glc) into glucose to be incorporated into glycogen via an α(1→4) glycosidic bond.

Specificity

Glycogen synthase Rabbit Recombinant mAb detects endogenous level of total glycogen synthase.

Background

Glycogen synthase (GS), a key enzyme in glycogen synthesis, is activated by the allosteric stimulator glucose-6-phosphate (G6P) and by dephosphorylation through inactivation of GS kinase-3 with insulin. It is a glycosyltransferase that catalyzes the conversion of the glucosyl (Glc) moiety of uridine diphosphate glucose (UDP-Glc) into glucose to be incorporated into glycogen via an α(1→4) glycosidic bond.

Usage Information

Application

WB, IHC,ELISA

Dilution

WB	IHC
1:1000	1:50

Reactivity

Human Mouse

MW (kDa)

85kDa

Source

Rabbit

Concentration

1mg/ml

Storage buffer

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

Storage
(From the date of receipt)

Store at –20°C.

References

[1] Bouskila M, et al. Cell Metab. 2010, 12(5):456-66.
[2] Palm DC, et al. FEBS J. 2013, 280(1):2-27.

Application Data

Validated by Selleck

IHC