GATA2/3 Rabbit Recombinant mAb

Catalog No.A5061

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Description

Specificity GATA2/3 Rabbit Recombinant mAb detects endogenous levels of total GATA2/3.
Background The GATA family of transcription factors, which contain zinc fingers in their DNA binding domain, have emerged as candidate regulators of gene expression in hematopoietic cells. Gata factors have been shown to be important in cell-fate specification as well as cell differentiation, proliferation, and movement during development. GATA2 is expressed in hematopoietic progenitors, including early erythroid cells, mast cells, and megakaryocytes, and also in nonhematopoietic embryonic stem cells. GATA3 expression is restricted to T-lymphocyte cells and some nonhematopoietic cell types, including embryonic stem cells.

Usage Information

Application WB, IF,ELISA
Dilution
WB IF
1:1000 1:50
Reactivity Human Mouse Rat
MW (kDa) 51kDa
Source Rabbit
Concentration 1mg/ml
Storage buffer 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
Storage
(From the date of receipt)
Store at –20°C.

Application Data

WB

Validated by Selleck

IF

Validated by Selleck