Econazole

Catalog No.S5492

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Technical Data

Formula

C18H15Cl3N2O

Molecular Weight 381.68 CAS No. 27220-47-9
Solubility (25°C)* In vitro DMSO 76 mg/mL (199.11 mM)
Ethanol '-1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

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Biological Activity

Description Econazole is a broad spectrum antimycotic with some action against Gram positive bacteria.

Protocol (from reference)

Selleck's Econazole Has Been Cited by 5 Publications

Suppression of TRPV5 Regulates Microglia-Mediated Neuroinflammation Following Status Epilepticus [ Glia, 2025, 73(11):2289-2304] PubMed: 40708193
Virtual screening and biological evaluation to identify pharmaceuticals potentially causing hypertension and hypokalemia by inhibiting steroid 11β-hydroxylase [ Toxicol Appl Pharmacol, 2023, 475:116638] PubMed: 37499767
Repurposing econazole as a pharmacological autophagy inhibitor to treat pancreatic ductal adenocarcinoma [ Acta Pharm Sin B, 2022, 12(7):3085-3102] PubMed: 35865101
Econazole nitrate reversed the resistance of breast cancer cells to Adriamycin through inhibiting the PI3K/AKT signaling pathway. [ Am J Cancer Res, 2020, 10(1):263-274] PubMed: 32064166
Econazole Induces p53-Dependent Apoptosis and Decreases Metastasis Ability in Gastric Cancer Cells [ Biomol Ther (Seoul), 2020, 25] PubMed: 32209732

RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.

SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.