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Technical Data
| Formula | C19H15N3O2 |
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| Molecular Weight | 317.34 | CAS No. | 125314-13-8 | |
| Solubility (25°C)* | In vitro | DMSO | 63 mg/mL (198.52 mM) | |
| Ethanol | 1 mg/mL (3.15 mM) | |||
| Water | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Preparing Stock Solutions
Biological Activity
| Description | CP21R7 is a potent and selective GSK-3β inhibitor that can potently activate canonical Wnt signalling. | |
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Protocol (from reference)
Selleck's CP21R7 has been cited by 11 publications
| Generating human artery and vein cells from pluripotent stem cells highlights the arterial tropism of Nipah and Hendra viruses [ Cell, 2022, 185(14):2523-2541.e30] | PubMed: 35738284 |
| Establishment and characterization of immortalized sweat gland myoepithelial cells [ Sci Rep, 2022, 12(1):7] | PubMed: 34997030 |
| Nanoprotein Interaction Atlas Reveals the Transport Pathway of Gold Nanoparticles across Epithelium and Its Association with Wnt/β-Catenin Signaling [ ACS Nano, 2021, 10.1021/acsnano.1c06452] | PubMed: 34672537 |
| Endothelial Progenitor Cells Produced From Human Pluripotent Stem Cells by a Synergistic Combination of Cytokines, Small Compounds, and Serum-Free Medium [ Front Cell Dev Biol, 2020, 15;8:309] | PubMed: 32509776 |
| Gastric-cancer-derived Mesenchymal Stem Cells: A Promising Target for Resveratrol in the Suppression of Gastric Cancer Metastasis [ Hum Cell, 2020, 29] | PubMed: 32350750 |
| Hyperin Controls the Development and Therapy of Gastric Cancer via Regulating Wnt/β-Catenin Signaling [ Cancer Manag Res, 2020, 12:11773-11782] | PubMed: 33235505 |
| Activation of Wnt/β-catenin Pathway Causes Insulin Resistance and Increases Lipogenesis in HepG2 Cells via Regulation of Endoplasmic Reticulum Stress [ Biochem Biophys Res Commun, 2020, 4;526(3):764-771] | PubMed: 32265032 |
| lncRNA-ATB Promotes Stemness Maintenance in Colorectal Cancer by Regulating Transcriptional Activity of the β-Catenin Pathway [ Exp Ther Med, 2020, 19(4):3097-3103] | PubMed: 32256798 |
| Robust differentiation of human pluripotent stem cells into endothelial cells via temporal modulation of ETV2 with modified mRNA [ Sci Adv, 2020, 6(30):eaba7606] | PubMed: 32832668 |
| TIPE1 Impairs Stemness Maintenance in Colorectal Cancer Through Directly Targeting β-catenin. [ Carcinogenesis, 2019, 10.1093/carcin/bgz079] | PubMed: 31111874 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.