Brilliant Blue G

Catalog No.S3217 Batch:S321702

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Technical Data

Formula
C47H48N3NaO7S2
Molecular Weight 854.02 CAS No. 6104-58-1
Solubility (25°C)* In vitro DMSO 100 mg/mL (117.09 mM)
Water 100 mg/mL (117.09 mM)
Ethanol 4 mg/mL (4.68 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Brilliant Blue G (BBG) is a dye which is commonly used in laboratories to stain or quantify proteins.Brilliant Blue G is a potent non-competitive antagonist of P2X7 receptor with IC50 of 10.1 nM and 265 nM for rat P2X7 and human P2X7, respectively.
Targets
rat P2X7 [1]
(Cell-free assay)
human P2X7 [1]
(Cell-free assay)
10.1 nM 265 nM

Protocol (from reference)

Selleck's Brilliant Blue G has been cited by 2 publications

CD39+ tumor infiltrating T cells from colorectal cancers exhibit dysfunctional phenotype [ Am J Cancer Res, 2024, 14(2):585-600] PubMed: 38455401
Upregulation of P2X7 Exacerbates Myocardial Ischemia-Reperfusion Injury through Enhancing Inflammation and Apoptosis in Diabetic Mice [ J Immunol, 2023, 210(12):1962-73] PubMed: 37144844

RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.