BL-918

Catalog No.S0819 Batch:S081901

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Technical Data

Formula

C23H15F8N3OS

Molecular Weight 533.44 CAS No. 2101517-69-3
Solubility (25°C)* In vitro DMSO 100 mg/mL (187.46 mM)
Ethanol 100 mg/mL (187.46 mM)
Water Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description BL-918 is a potent, orally active activator of UNC-51-like kinase 1 (ULK1) with EC50 of 24.14 nM and Kd of 0.719 μM. BL-918 induces cytoprotective autophagy for Parkinson's disease treatment.
Targets
ULK1 [1]
(Cell-free assay)
ULK1 [1]
(Cell-free assay)
24.14 nM(EC50) 0.719 μM(Kd)

Protocol (from reference)

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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.