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Technical Data
| Formula | C14H12N2 |
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| Molecular Weight | 208.26 | CAS No. | 621-72-7 | |
| Solubility (25°C)* | In vitro | DMSO | 42 mg/mL (201.67 mM) | |
| Ethanol | 42 mg/mL (201.67 mM) | |||
| Water | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Preparing Stock Solutions
Biological Activity
| Description | Bendazol (2-Benzylbenzimidazole, Dibazol, Dibazole, Bendazole, Tromasedan) is a hypotensive drug that enhances NO synthase activity in renal glomeruli and collecting tubules. Bendazol inhibits the progression of form-deprivation myopia (FDM) and suppresses the upregulation of HIF-1α. | ||
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| Targets |
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| In vivo | Bendazol enhances NO synthase activity in renal glomeruli and collecting tubules, but this effect is less pronounced and short lasting. During the first week after injection of bendazol, insignificant elevation of NO synthase activity is observed in the proximal nephron segments.[1] |
Protocol (from reference)
| Animal Study: |
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References
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
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