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Description
| Specificity | ATF4 Rabbit Recombinant mAb detects endogenous level of total ATF4. |
|---|---|
| Background | Activating transcription factor 4 (ATF4), a member of the ATF/CREB transcription factor family, is an important factor that participates in several pathophysiological processes such as the stress response, bone resorption, medullary hematopoiesis and lens formation. It forms homodimers and heterodimers with other transcription factors, including some members of the AP-1 family. ATF4 acts as a transcription activator and inhibitor. Its activity is primarily regulated at the post-transcriptionally level, especially the translation of ATF4 mRNA. The protein degrades quickly, and its half-life is only 30-60 min. |
Usage Information
| Application | WB, IF,ELISA | ||||
|---|---|---|---|---|---|
| Dilution |
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| Reactivity | Human Mouse Rat | ||||
| MW (kDa) | 50kDa | ||||
| Source | Rabbit | ||||
| Concentration | 1mg/ml | ||||
| Storage buffer | 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. | ||||
| Storage (From the date of receipt) |
Store at –20°C. |
Application Data
WB
Validated by Selleck
IF