Aromatase Rabbit Recombinant mAb

Catalog No.A5282

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Description

Specificity Aromatase Rabbit Recombinant mAb detects endogenous level of total Aromatase.
Background Aromatase is the key enzyme for estrogen biosynthesis. It is localized in the endoplasmic reticulum of estrogen-producing cells. Aromatase enzyme complex is comprised of two polypeptides. The first of these is a specific cytochrome P450 (P450), namely aromatase cytochrome P450 (P450arom) (the product of the CYP19 gene). The second is a flavoprotein, NADPH-cytochrome P450 reductase and is ubiquitously distributed in most cells. Cell-specific expression of P450arom determines the presence or absence of aromatase activity.

Usage Information

Application WB, IHC,ELISA
Dilution
WB IHC
1:1000 1:50
Reactivity Human Rat
MW (kDa) 53kDa
Source Rabbit
Concentration 1mg/ml
Storage buffer 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
Storage Store at –20°C.

Application Data

WB

Validated by Selleck

IHC

Validated by Selleck