Anti-mouse PD-L1 (B7-H1)-InVivo

Catalog No.A2115        Batch: A211549

       Clone No.10F.9G2

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Anti-mouse PD-L1 (B7-H1)-InVivo (Clone:10F.9G2) monoclonal antibody reacts with mouse PD-L1 (also known as B7-H1, CD274). The 10F.9G2 antibody has been shown to block the interaction between PD-L1 and PD-1 and between PD-L1 and B7-1 (CD80).

Technical Data

Formulation PBS Buffer, PH 7.4
Clone 10F.9G2
Immunogen Mouse CD274
Isotype Rat,IgG2b, κ
Application in vivo PD-L1 blockade,IHC (frozen),FCM
Source CHO
Murine Pathogen Screening Panel all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus.
Storage
(From the date of receipt)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Sterility 9.69 mg/ml
Purity 99%
Protein concentration 9.69 mg/ml
Endotoxin Level ＜1EU/mg

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Selleck's Anti-mouse PD-L1 (B7-H1)-InVivo Has Been Cited by 54 publications

PRMT3 Drives IDO1-Dependent Radioresistance and Immunosuppression by Promoting Kynurenine Metabolism in Non-Small Cell Lung Cancer [ Cancer Research, October 23, 2025, 86(2):421-437]

https://www.ncbi.nlm.nih.gov/pubmed/?term=41129671
Noninvasive Immunotyping and Immunotherapy Monitoring of Lung Cancers via Nuclear Imaging of LAG-3 and PD-L1 [ Advanced Science, November 8, 2024, 12(1):e2404231]

https://www.ncbi.nlm.nih.gov/pubmed/?term=39513410
Silencing PCSK9 reshapes the spatiotemporal activation of STING for safe and effective cancer immunotherapy [ Nature Communications, November 25, 2025, 16(1):11622]

https://www.ncbi.nlm.nih.gov/pubmed/?term=41290746
Tetraspanin 13 Enhances Immune Evasion in Breast Cancer by Promoting MHC-I Degradation [ Cancer Research, November 11, 2025, 86(4):972-987]

https://www.ncbi.nlm.nih.gov/pubmed/?term=41218148
Simvastatin overcomes the pPCK1‐pLDHA‐SPRINGlac axis‐mediated ferroptosis and chemo‐immunotherapy resistance in AKT‐hyperactivated intrahepatic cholangiocarcinoma [ Cancer Communications, May 29, 2025, 45(8):1038-1071]

https://www.ncbi.nlm.nih.gov/pubmed/?term=40443016
Mannose-binding lectin 2 secreted by hepatocellular carcinoma cells recruits and activates natural killer cells to reshape an immune-activated microenvironment [ PLOS Biology, May 20, 2026, 24(5):e3003793]

https://www.ncbi.nlm.nih.gov/pubmed/?term=42160305
An SPP1-SOCS1 pathway constrains interferon responses in tumor-associated macrophages and shapes an immunosuppressive tumor microenvironment [ Immunity, May 1, 2026, 59(5):1422-1437.e9]

https://www.ncbi.nlm.nih.gov/pubmed/?term=42049035
Oncolytic virus M1 reinvigorates CD8+ T-cell immunity against glioblastoma through B-cell-dependent antigen cross-presentation in the spleen [ Cellular and Molecular Immunology, March 4, 2026, 23(4):349-366]

https://www.ncbi.nlm.nih.gov/pubmed/?term=41781696
Immune-modified exosome vaccine loaded with liver cancer epitope peptides induces potent and specific antitumor immunity [ Journal of Nanobiotechnology, March 24, 2026, 24(1):411]

https://www.ncbi.nlm.nih.gov/pubmed/?term=41877229
An immunomodulatory photosensitizer-mediated photodynamic therapy synergizes with PD-L1 blockade against metastatic triple-negative breast cancer [ Frontiers in Pharmacology, July 17, 2025, 16:1651165]

https://www.ncbi.nlm.nih.gov/pubmed/?term=40746718

FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS.

Specific storage and handling information for each product is indicated on the product datasheet. Most Selleck products are stable under the recommended conditions. Products are sometimes shipped at a temperature that differs from the recommended storage temperature. Short-term storage of many products are stable in the short-term at temperatures that differ from that required for long-term storage.
We ensure that the product is shipped under conditions that will maintain the quality of the reagents. Upon receipt of the product, follow the storage recommendations on the product data sheet.