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Anti-mouse PD-L1 (B7-H1)-InVivo
Catalog No.A2115 Batch: A211546
Clone No.10F.9G2
Anti-mouse PD-L1 (B7-H1)-InVivo (Clone:10F.9G2) monoclonal antibody reacts with mouse PD-L1 (also known as B7-H1, CD274). The 10F.9G2 antibody has been shown to block the interaction between PD-L1 and PD-1 and between PD-L1 and B7-1 (CD80).
Technical Data
| Formulation | PBS Buffer, PH 7.4 |
|---|---|
| Clone | 10F.9G2 |
| Immunogen | Mouse CD274 |
| Isotype | Rat,IgG2b, κ |
| Application | in vivo PD-L1 blockade,IHC (frozen),FCM |
| Source | CHO |
| Murine Pathogen Screening Panel | all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus. |
| Storage (From the date of receipt) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles |
| Sterility | 7.26 mg/ml |
| Purity | 99% |
| Protein concentration | 7.26 mg/ml |
| Endotoxin Level | ＜1EU/mg |
Customer Product Validation
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Data from [Data independently produced by , ]
Selleck's Anti-mouse PD-L1 (B7-H1)-InVivo Has Been Cited by 54 publications
| PRMT3 Drives IDO1-Dependent Radioresistance and Immunosuppression by Promoting Kynurenine Metabolism in Non-Small Cell Lung Cancer [ Cancer Research, October 23, 2025, 86(2):421-437] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=41129671 |
| Noninvasive Immunotyping and Immunotherapy Monitoring of Lung Cancers via Nuclear Imaging of LAG-3 and PD-L1 [ Advanced Science, November 8, 2024, 12(1):e2404231] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=39513410 |
| Silencing PCSK9 reshapes the spatiotemporal activation of STING for safe and effective cancer immunotherapy [ Nature Communications, November 25, 2025, 16(1):11622] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=41290746 |
| Tetraspanin 13 Enhances Immune Evasion in Breast Cancer by Promoting MHC-I Degradation [ Cancer Research, November 11, 2025, 86(4):972-987] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=41218148 |
| Simvastatin overcomes the pPCK1‐pLDHA‐SPRINGlac axis‐mediated ferroptosis and chemo‐immunotherapy resistance in AKT‐hyperactivated intrahepatic cholangiocarcinoma [ Cancer Communications, May 29, 2025, 45(8):1038-1071] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=40443016 |
| Mannose-binding lectin 2 secreted by hepatocellular carcinoma cells recruits and activates natural killer cells to reshape an immune-activated microenvironment [ PLOS Biology, May 20, 2026, 24(5):e3003793] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=42160305 |
| An SPP1-SOCS1 pathway constrains interferon responses in tumor-associated macrophages and shapes an immunosuppressive tumor microenvironment [ Immunity, May 1, 2026, 59(5):1422-1437.e9] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=42049035 |
| Oncolytic virus M1 reinvigorates CD8+ T-cell immunity against glioblastoma through B-cell-dependent antigen cross-presentation in the spleen [ Cellular and Molecular Immunology, March 4, 2026, 23(4):349-366] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=41781696 |
| Immune-modified exosome vaccine loaded with liver cancer epitope peptides induces potent and specific antitumor immunity [ Journal of Nanobiotechnology, March 24, 2026, 24(1):411] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=41877229 |
| An immunomodulatory photosensitizer-mediated photodynamic therapy synergizes with PD-L1 blockade against metastatic triple-negative breast cancer [ Frontiers in Pharmacology, July 17, 2025, 16:1651165] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=40746718 |
FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS.
Specific storage and handling information for each product is indicated on the product datasheet. Most Selleck products are stable under the recommended conditions. Products are sometimes shipped at a temperature that differs from the recommended storage temperature. Short-term storage of many products are stable in the short-term at temperatures that differ from that required for long-term storage.
We ensure that the product is shipped under conditions that will maintain the quality of the reagents. Upon receipt of the product, follow the storage recommendations on the product data sheet.