Toll Free: (877) 796-6397 -- USA and Canada only -- |
Fax: +1-832-582-8590 Orders: +1-832-582-8158 |
Tech Support: +1-832-582-8158 Ext:3 Please provide your Order Number in the email. |
Catalog No.A2115 Batch: A211535
Clone No.10F.9G2
Anti-mouse PD-L1 (B7-H1)-InVivo (Clone:10F.9G2) monoclonal antibody reacts with mouse PD-L1 (also known as B7-H1, CD274). The 10F.9G2 antibody has been shown to block the interaction between PD-L1 and PD-1 and between PD-L1 and B7-1 (CD80).
Formulation | PBS Buffer, PH 7.4 |
---|---|
Clone | 10F.9G2 |
Immunogen | Mouse CD274 |
Isotype | Rat,IgG2b, κ |
Application | in vivo PD-L1 blockade,IHC (frozen),FCM |
Source | CHO |
Storage (From the date of receipt) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles |
Sterility | 7.60 mg/mL |
Purity | 99% |
Protein concentration | 7.60 mg/mL |
Endotoxin Level | <1 EU/mg |
Data from [Data independently produced by , ]
Simvastatin overcomes the pPCK1-pLDHA-SPRINGlac axis-mediated ferroptosis and chemo-immunotherapy resistance in AKT-hyperactivated intrahepatic cholangiocarcinoma [ Cancer Commun (Lond), 2025, 10.1002/cac2.70036] | PubMed: 40443016 |
Non-canonical PRC1.1 licenses transcriptional response to enable Treg plasticity in immune adaptation [ Mol Cell, 2025, 85(13):2517-2534.e6] | PubMed: 40527320 |
NRIR promotes immune escape in hepatocellular cancer by regulating IFNγ-induced PD-L1 expression [ J Adv Res, 2025, S2090-1232(25)00133-X] | PubMed: 40023249 |
Faecalibacterium prausnitzii promotes anti-PD-L1 efficacy in natural killer/T-cell lymphoma by enhancing antitumor immunity [ BMC Med, 2025, 23(1):387] | PubMed: 40597177 |
Tumor microenvironment-associated oxidative stress impairs SIRT1 secretion to suppress anti-tumor immune response [ Cell Rep, 2025, 44(5):115679] | PubMed: 40343797 |
Lipin1-dependent transcriptional inactivation of SREBPs contributes to selinexor sensitivity in multiple myeloma [ Acta Pharmacol Sin, 2025, 10.1038/s41401-025-01553-3] | PubMed: 40229499 |
ENTPD8 overexpression enhances anti-PD-L1 therapy in hepatocellular carcinoma via miR-214-5p inhibition [ iScience, 2025, 28(2):111819] | PubMed: 39995876 |
Interleukin-17A facilitates tumor progression via upregulating programmed death ligand-1 expression in hepatocellular carcinoma [ World J Gastrointest Oncol, 2025, 17(1):97831] | PubMed: 39817127 |
Asiaticoside enhances the anti-tumor effect of anti-PDL1 by regulating T cell activity through increasing LCK activity [ Pathol Res Pract, 2025, 271:155995] | PubMed: 40373489 |
Metabolic landscape of head and neck squamous cell carcinoma informs a novel kynurenine/Siglec-15 axis in immune escape [ Cancer Commun (Lond), 2024, 10.1002/cac2.12545] | PubMed: 38734931 |
FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS.
Specific storage and handling information for each product is indicated on the product datasheet. Most Selleck products are stable under the recommended conditions. Products are sometimes shipped at a temperature that differs from the recommended storage temperature. Short-term storage of many products are stable in the short-term at temperatures that differ from that required for long-term storage.
We ensure that the product is shipped under conditions that will maintain the quality of the reagents. Upon receipt of the product, follow the storage recommendations on the product data sheet.