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Anti-mouse PD-1 (CD279)-InVivo
Catalog No.A2122 Batch: A212275
Clone No.RMP1-14
Anti-mouse PD-1 (CD279)-InVivo(Clone:RMP1-14) reacts with mouse PD-1 (programmed death-1) also known as CD279. PD-1 is a 50-55 kDa cell surface receptor encoded by the Pdcd1 gene that belongs to the CD28 family of the Ig superfamily.
Technical Data
| Formulation | PBS Buffer, PH 7.4 |
|---|---|
| Clone | RMP1-14 |
| Isotype | Rat IgG2a, κ |
| Application | in vivo blocking of PD-1/PD-L signaling |
| Source | CHO |
| Murine Pathogen Screening Panel | all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus. |
| Storage (From the date of receipt) |
Store the undiluted solution at 4°C and avoid freeze-thaw cycle |
| Sterility | 8.37 mg/ml |
| Purity | 99% |
| Protein concentration | 8.37 mg/ml |
| Endotoxin Level | ＜1EU/mg |
Customer Product Validation
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Selleck's Anti-mouse PD-1 (CD279)-InVivo Has Been Cited by 78 publications
| Co-inhibition of PGF and VEGFA enhances the effectiveness of immunotherapy in bladder cancer [ International Journal of Medical Sciences, October 28, 2024, 21(15):2870-2882] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=39628692 |
| EIF2B4 promotes hepatocellular carcinoma progression and immune evasion by driving STAT3 translation via a GEF-dependent mechanism [ Cellular Oncology, October 27, 2025, 48(6):1919-1933] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=41144132 |
| Characteristics of tertiary lymphoid structures in prostate cancer and the impact of neoadjuvant therapy on their formation and maturation [ Frontiers in Immunology, November 4, 2025, 16:1663396] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=41262256 |
| Yin Yang 1 Promotes Antiprogrammed Cell Death-1 Resistance in Hepatocellular Carcinoma through Polypeptide N-Acetylgalactosaminyltransferase 16-Mediated Glycosylation of Programmed Death Ligand-1 [ MedComm, November 26, 2025, 6(12):e70504] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=41322030 |
| ZDHHC3-mediated SCAP S-acylation promotes cholesterol biosynthesis and tumor immune escape in hepatocellular carcinoma [ Cell Reports, November 1, 2024, 43(11):114962] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=39522165 |
| Low-dose radiotherapy synergizes with PD-1 blockade to achieve durable survival in advanced NSCLC through antitumor neutrophil programming [ Signal Transduction and Targeted Therapy, May 7, 2026, 11(1):170] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=42091852 |
| Betrixaban activates cGAS-STING to promote antitumor immunity without pathological inflammation [ EMBO Molecular Medicine, May 14, 2026, 18(6):2213-2235] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=42135568 |
| CDK4/6 inhibitor abemaciclib combined with low-dose radiotherapy enhances the anti-tumor immune response to PD-1 blockade by inflaming the tumor microenvironment in Rb-deficient small cell lung cancer [ Translational Lung Cancer Research, May 1, 2024, 13(5):1032-1046] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=38854937 |
| CCL5 hi CD4 + T Cells Regulate Macrophage Polarization and Promote Immunotherapy Response in Bladder Cancer [ Cancer Immunology Research, May 04, 2026, nan] | |
| Oncolytic virus M1 reinvigorates CD8+ T-cell immunity against glioblastoma through B-cell-dependent antigen cross-presentation in the spleen [ Cellular and Molecular Immunology, March 4, 2026, 23(4):349-366] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=41781696 |
FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS.
Specific storage and handling information for each product is indicated on the product datasheet. Most Selleck products are stable under the recommended conditions. Products are sometimes shipped at a temperature that differs from the recommended storage temperature. Short-term storage of many products are stable in the short-term at temperatures that differ from that required for long-term storage.
We ensure that the product is shipped under conditions that will maintain the quality of the reagents. Upon receipt of the product, follow the storage recommendations on the product data sheet.