Anti-mouse NK1.1-InVivo

Catalog No.A2114        Batch: A211416

       Clone No.PK136

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The PK136 monoclonal antibody(Clone: PK136) reacts with mouse NK1.1 also known as CD161b/CD161c, KLRB1, NKR-P1A and Ly-55.

Technical Data

Formulation PBS buffer, pH 7.0
Clone PK136
Immunogen Mouse spleen and bone marrow cells enriched for NK1+ cells
Isotype Mouse IgG2a,κ
Application in vivo NK cell depletion,FCM
Source CHO
Murine Pathogen Screening Panel all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus.
Storage
(From the date of receipt)
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Sterility 7.23 mg/ml
Purity 99%
Protein concentration 7.23 mg/ml
Endotoxin Level <1EU/mg

Customer Product Validation

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Selleck's Anti-mouse NK1.1-InVivo Has Been Cited by 15 publications

Silencing PCSK9 reshapes the spatiotemporal activation of STING for safe and effective cancer immunotherapy [ Nature Communications, November 25, 2025, 16(1):11622]

https://www.ncbi.nlm.nih.gov/pubmed/?term=41290746

Epidermal MHC-II-mediated NK cell recruitment triggers keratinocyte pyroptosis, facilitating pathogenesis of psoriasis [ Experimental & Molecular Medicine, May 8, 2026, 58(5):1573-1588]

https://www.ncbi.nlm.nih.gov/pubmed/?term=42104015

A Probiotic Approach Targeting Hypersialylation Revives CD8+ T-cell Immunity and Boosts Photodynamic Therapy Efficacy in Solid Tumors [ Cancer Research, May 14, 2026, 2915-2934]

https://www.ncbi.nlm.nih.gov/pubmed/?term=42133438

A Probiotic Approach Targeting Hypersialylation Revives CD8+ T-cell Immunity and Boosts Photodynamic Therapy Efficacy in Solid Tumors [ Cancer Research, May 14, 2026, OF1-OF20]

https://www.ncbi.nlm.nih.gov/pubmed/?term=42133438

Efficacy of intranasal adenovirus vector vaccine is attenuated by type I IFN-induced NK cell activation [ Molecular Therapy Advances, June 1, 2026, 34(2):201742]

https://www.ncbi.nlm.nih.gov/pubmed/?term=42164241

NK cell-derived GZMB (granzyme B) suppresses glioblastoma radioresistance by blocking SDC1-mediated autophagosome maturation [ Autophagy, January 9, 2026, 22(3):545-566]

https://www.ncbi.nlm.nih.gov/pubmed/?term=41378763

Enhancing oncolytic virotherapy with a tri-specific T-cell engager targeting CD3ε, EpCaM, and 4-1BB: preclinical evaluation and implications for cancer immunotherapy [ BMC Medicine, January 30, 2026, 127]

https://www.ncbi.nlm.nih.gov/pubmed/?term=41612317

Enhancing oncolytic virotherapy with a tri-specific T-cell engager targeting CD3ε, EpCaM, and 4-1BB: preclinical evaluation and implications for cancer immunotherapy [ BMC Medicine, January 30, 2026, 24(1):127]

https://www.ncbi.nlm.nih.gov/pubmed/?term=41612317

Glycoliposomes target lymphatic dendritic cells in a size-dependent manner to activate natural killer T cells against breast tumors [ Journal of Controlled Release, December 1, 2025, 388:114274]

https://www.ncbi.nlm.nih.gov/pubmed/?term=41016478

Selective Depletion of CCR8+Treg Cells Enhances the Antitumor Immunity of Cytotoxic T Cells in Lung Cancer by Dendritic Cells [ Journal of Thoracic Oncology, August 1, 2025, 20(8):1050-1074]

https://www.ncbi.nlm.nih.gov/pubmed/?term=40056978

FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS.

Specific storage and handling information for each product is indicated on the product datasheet. Most Selleck products are stable under the recommended conditions. Products are sometimes shipped at a temperature that differs from the recommended storage temperature. Short-term storage of many products are stable in the short-term at temperatures that differ from that required for long-term storage.
We ensure that the product is shipped under conditions that will maintain the quality of the reagents. Upon receipt of the product, follow the storage recommendations on the product data sheet.