Anti-mouse IL-17A-InVivo [17F3]

Catalog No.A2120        Batch: A212008

       Clone No.17F3

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Anti-mouse IL-17A-InVivo monoclonal antibody (Clone:17F3) reacts with mouse IL-17A which is a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. Anti-mouse IL-17A-InVivo has been shown to neutralize IL-17A in vivo.

Technical Data

Formulation PBS Buffer, PH 7.4
Clone 17F3
Immunogen Mouse IL-17A cross-linked to OVA
Isotype Mouse IgG1, κ
Application in vivo IL-17A neutralization
Source CHO
Murine Pathogen Screening Panel all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus.
Storage
(From the date of receipt)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.
Sterility 4.75 mg/ml
Purity 99%
Protein concentration 4.75 mg/ml
Endotoxin Level ＜1EU/mg

Customer Product Validation

Verified customer review of Anti-mouse IL-17A-InVivo [17F3]

Selleck's Anti-mouse IL-17A-InVivo [17F3] Has Been Cited by 23 publications

Keratinocyte-specific H4K12 lactylation drives a non-canonical IL-17-dependent signaling in psoriasis progression in mice [ Nature Communications, September 30, 2025, 16(1):8639]

https://www.ncbi.nlm.nih.gov/pubmed/?term=41027887
Cardiac arrest triggers IL-17-mediated neuroinflammation and astrocyte polarization: insights into pathogenesis and intervention [ Journal of Neuroinflammation, November 14, 2025, 22(1):268]

https://www.ncbi.nlm.nih.gov/pubmed/?term=41239323
Analysis and experimental validation of IL-17 pathway and key genes as central roles associated with inflammation in hepatic ischemia-reperfusion injury [ Scientific Reports, March 18, 2024, 14(1):6423]

https://www.ncbi.nlm.nih.gov/pubmed/?term=38494504
Scleroglucan protects the intestine from irradiation-induced injury by targeting the IL-17 signaling pathway [ International Immunopharmacology, March 1, 2024, 129:111614]

https://www.ncbi.nlm.nih.gov/pubmed/?term=38350358
IL-17 Signaling Pathway: A Potential Signaling Pathway Mediating Neuroinflammation Induced by PM 2.5 [ Environment & Health, June 3, 2026, nan]
The IL-17A/Neutrophil axis plays a critical role in lethal infection induced by an emerging ultra-virulent Streptococcus suis serotype 5 strain [ Virulence, June 21, 2026, 17(1)]

https://www.ncbi.nlm.nih.gov/pubmed/?term=42308351
Fungal pathogen-responsive Th17 cells in gut-mouth axis enhance protection against oropharyngeal candidiasis [ iScience, June 1, 2025, 28(6):112675]

https://www.ncbi.nlm.nih.gov/pubmed/?term=40510134
Engineered probiotics platform for oral delivery of antibody as a high-compliance alternative for immune-mediated inflammatory diseases [ Cell Reports Medicine, January 1, 2026, 7(1):102523]

https://www.ncbi.nlm.nih.gov/pubmed/?term=41421354
Immunotherapy-induced sialadenitis: sjögren’s syndrome or a new sialadenitis [ Frontiers in Immunology, February 27, 2026, 17:1755419]

https://www.ncbi.nlm.nih.gov/pubmed/?term=41836391
Th17 cells/IL-17A shape Pasteurella multocida serotype A infection in murine and rabbit models [ Veterinary Research, December 16, 2025, 56(1):229]

https://www.ncbi.nlm.nih.gov/pubmed/?term=41402924

FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS.

Specific storage and handling information for each product is indicated on the product datasheet. Most Selleck products are stable under the recommended conditions. Products are sometimes shipped at a temperature that differs from the recommended storage temperature. Short-term storage of many products are stable in the short-term at temperatures that differ from that required for long-term storage.
We ensure that the product is shipped under conditions that will maintain the quality of the reagents. Upon receipt of the product, follow the storage recommendations on the product data sheet.