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Anti-mouse CD4-InVivo
Catalog No.A2101 Batch: A210128
Clone No.GK1.5
Anti-mouse CD4 antibody(Clone: GK1.5) reacts with mouse CD4, which is a 55 kDa cell surface type I membrane glycoprotein. CD4 is a co-receptor of the T cell receptor (TCR) and assists the latter in communicating with antigen-presenting cells.
Technical Data
| Formulation | PBS buffer, pH 6.5 |
|---|---|
| Clone | GK1.5 |
| Immunogen | Mouse CTL clone V4 |
| Isotype | Rat IgG2b,κ |
| Application | In vivo CD4+ T cell depletion,FCM,WB |
| Source | CHO |
| Murine Pathogen Screening Panel | all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus. |
| Storage (From the date of receipt) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles |
| Sterility | 9.80 mg/ml |
| Purity | 99% |
| Protein concentration | 9.80 mg/ml |
| Endotoxin Level | ＜1EU/mg |
Customer Product Validation
Selleck's Anti-mouse CD4-InVivo Has Been Cited by 49 publications
| FLT3L combined with GM-CSF induced dendritic cells drive broad tumor-specific CD8+ T cell responses and remodel the tumor microenvironment to enhance anti-tumor efficacy [ Frontiers in Immunology, September 4, 2025, 16:1649891] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=40977690 |
| Spatiotemporal Analysis of Mesenchymal Stem Cells Fate Determination by Inflammatory Niche Following Soft Tissue Injury at a Single‐Cell Level [ Advanced Science, September 23, 2024, 11(43):2310282] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=39308190 |
| LZTR1 regulates epithelial MHC-I expression via NF-κB1 to modulate CD8+ T cells activation [ Cell Discovery, October 29, 2025, 11(1):84] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=41162356 |
| TREM2-Mediated Cholesterol Efflux in Macrophages Inhibits Anti-Tumor Immunity via Limitation of CD4+ T and NK Cells [ Advanced Science, October 20, 2025, 13(5):e06995] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=41114464 |
| Oncolytic virus M1 functions as a bifunctional checkpoint inhibitor to enhance the antitumor activity of DC vaccine [ Cell Reports Medicine, October 1, 2023, 4(10):101229] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=37820722 |
| Silencing PCSK9 reshapes the spatiotemporal activation of STING for safe and effective cancer immunotherapy [ Nature Communications, November 25, 2025, 16(1):11622] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=41290746 |
| Low-dose radiotherapy combined with dual PD-L1 and VEGFA blockade elicits antitumor response in hepatocellular carcinoma mediated by activated intratumoral CD8+ exhausted-like T cells [ Nature Communications, November 24, 2023, 14(1):7709] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=38001101 |
| DOCK2 protects against bacterial sepsis by constraining T helper 1 response [ Frontiers in Immunology, May 29, 2025, 16:1527934] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=40510337 |
| Anti-BCL2 therapy eliminates giant congenital melanocytic nevus by senolytic and immune induction [ Signal Transduction and Targeted Therapy, May 16, 2025, 10(1):161] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=40374605 |
| HFB301001, an OX40-based immunotherapy, drives Treg clearance and CTL activation through optimized OX40 receptor clustering [ Journal for ImmunoTherapy of Cancer, March 30, 2026, e014185] |
https://www.ncbi.nlm.nih.gov/pubmed/?term=41912269 |
FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS.
Specific storage and handling information for each product is indicated on the product datasheet. Most Selleck products are stable under the recommended conditions. Products are sometimes shipped at a temperature that differs from the recommended storage temperature. Short-term storage of many products are stable in the short-term at temperatures that differ from that required for long-term storage.
We ensure that the product is shipped under conditions that will maintain the quality of the reagents. Upon receipt of the product, follow the storage recommendations on the product data sheet.