Anti-human/mouse TGF-β-InVivo

Catalog No.A2113 Batch: A211310

Clone No.1D11.16.8

The 1D11.16.8 monoclonal antibody reacts with mouse, human, rat, monkey, hamster, canine and bovine TGF-β (transforming growth factor beta) isoforms 1, 2 and 3.The 1D11.16.8 monoclonal antibody is a neutralizing antibody.

Technical Data

Formulation	PBS buffer, pH 7.0
Clone	1D11.16.8
Immunogen	Bovine TGFβ isoform 2
Isotype	Mouse IgG1,κ
Application	in vivo/vitro TGFβ neutralization,WB
Source	CHO
Murine Pathogen Screening Panel	all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus.
Storage (From the date of receipt)	Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
Sterility	7.88 mg/ml
Purity	99%
Protein concentration	7.88 mg/ml
Endotoxin Level	＜1EU/mg

Selleck's Anti-human/mouse TGF-β-InVivo Has Been Cited by 10 publications

Single-cell and spatial dissection of precancerous lesions underlying the initiation process of oral squamous cell carcinoma [ Cell Discovery, March 13, 2023, 9(1):28]	https://www.ncbi.nlm.nih.gov/pubmed/?term=36914617
HBx hijacks the miR‐19a‐3p/BAMBI/TGF‐β1 axis to impair the anti‐tumour activity of CD4 + T cells in diffuse large B‐cell lymphoma [ Clinical and Translational Medicine, January 1, 2026, 16(1):e70578]	https://www.ncbi.nlm.nih.gov/pubmed/?term=41492119
Downregulated Smad3 signaling impairs the maturation of MO-MDSC in colorectal cancer [ Cell Death & Disease, December 8, 2025, 16(1):880]	https://www.ncbi.nlm.nih.gov/pubmed/?term=41360769
Colorectal Cancer Cells Promote de novo Glycine Synthesis for Collagen Production in Cancer‐Associated Fibroblasts by Secreting TGF‐β1 [ MedComm – Oncology, August 24, 2025, 4(3):e70037]
Depletion of macrophages during early postnatal development leads to disrupted tooth root development and altered Gli1⁺ MSC trajectory [ Cell Death & Disease, April 26, 2026, 17(1):555]	https://www.ncbi.nlm.nih.gov/pubmed/?term=42036413
HBx hijacks the miR-19a-3p/BAMBI/TGF-β1 axis to impair the anti-tumour activity of CD4+ T cells in diffuse large B-cell lymphoma [ Clinical and Translational Medicine, 2026, e70578]	https://www.ncbi.nlm.nih.gov/pubmed/?term=41492119
Pre-Clinical Assessment of SAR442257, a CD38/CD3xCD28 Trispecific T Cell Engager in Treatment of Relapsed/Refractory Multiple Myeloma [ Cells, 2024, 13(10)879]	https://www.ncbi.nlm.nih.gov/pubmed/?term=38786100
Pre-Clinical Assessment of SAR442257, a CD38/CD3xCD28 Trispecific T Cell Engager in Treatment of Relapsed/Refractory Multiple Myeloma [ Cells, 2024, 879]	https://www.ncbi.nlm.nih.gov/pubmed/?term=38786100
Single-cell and spatial dissection of precancerous lesions underlying the initiation process of oral squamous cell carcinoma [ Cell Discov, 2023, 9(1):28]	https://www.ncbi.nlm.nih.gov/pubmed/?term=36914617
Single-cell and spatial dissection of precancerous lesions underlying the initiation process of oral squamous cell carcinoma [ Cell Discovery, 2023, 28]	https://www.ncbi.nlm.nih.gov/pubmed/?term=36914617

FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS.

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We ensure that the product is shipped under conditions that will maintain the quality of the reagents. Upon receipt of the product, follow the storage recommendations on the product data sheet.