Annexin A10 Rabbit Recombinant mAb

Catalog No.A5338

Description

Specificity	Annexin A10 Rabbit Recombinant mAb detects endogenous level of total annexin A10.
Background	Annexin A10 (ANXA10) is a calcium- and phospholipid-binding protein expressed normally inthe gastric mucosa. Biochemically, annexins are defined as soluble, hydrophilic proteins that bind to negatively charged phospholipids in a Ca²⁺-dependent manner. This binding is reversible. Downregulation of annexin A10 was correlated with dedifferentiation, invasion, and tumor progression, pointing to a possible tumor suppressor role.

Specificity

Annexin A10 Rabbit Recombinant mAb detects endogenous level of total annexin A10.

Background

Annexin A10 (ANXA10) is a calcium- and phospholipid-binding protein expressed normally inthe gastric mucosa. Biochemically, annexins are defined as soluble, hydrophilic proteins that bind to negatively charged phospholipids in a Ca²⁺-dependent manner. This binding is reversible. Downregulation of annexin A10 was correlated with dedifferentiation, invasion, and tumor progression, pointing to a possible tumor suppressor role.

Usage Information

Application

WB, IHC,ELISA

Dilution

WB	IHC
1:1000	1:50

Reactivity

Human Mouse Rat

MW (kDa)

37kDa

Source

Rabbit

Concentration

1mg/ml

Storage buffer

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

Storage
(From the date of receipt)

Store at –20°C.

References

[1] Lu SH, et al. Histopathology. 2013, 63(5):640-8.
[2] Gerke V, et al. Physiol Rev. 2002, 82(2):331-71.
[3] Quiskamp N, et al. Cell Mol Life Sci. 2014, 71(2):311-29.

Application Data

Validated by Selleck

IHC