Aminoxyacetic acid

Catalog No.E0859 Batch:E085901

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Technical Data

Formula

C2H5NO3

Molecular Weight 91.07 CAS No. 645-88-5
Solubility (25°C)* In vitro DMSO 2 mg/mL (21.96 mM)
Water 2 mg/mL (21.96 mM)
Ethanol 2 mg/mL (21.96 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Aminoxyacetic acid (AOAA) is an inhibitor of malate–aspartate shuttle (MAS) that effectively suppresses MAS activity in cells. It also induces both early‑ and late‑stage apoptosis of resting and LPS‑activated microglia and impairs their energy metabolism. Aminoxyacetic acid is also an inhibitor of aminobutyrate aminotransferase and CBS (cystathionine β-synthase).

Protocol (from reference)

References

  • https://pubmed.ncbi.nlm.nih.gov/25998884/

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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.