Alpha-Estradiol

Catalog No.S5910 Batch:S591001

Print

Technical Data

Formula

C18H24O2

Molecular Weight 272.38 CAS No. 57-91-0
Solubility (25°C)* In vitro DMSO 54 mg/mL (198.25 mM)
Ethanol 54 mg/mL (198.25 mM)
Water Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Alpha-Estradiol (α-Estradiol, 17 alpha-Estradiol, Alfatradiol, Epiestradiol, Epiestrol, Alora, 17 α-E2), a natural, non-feminizing stereoisomer, a hormonally almost inactive isomer of physiological 17 beta-estradiol (17 β-E2), is a weak inhibitor of estrogen.
Targets
estrogen [1]
In vivo

α-estradiol regulates the MAPK pathways involved in intracellular signaling and inflammation.[2]

Protocol (from reference)

Animal Study:

[2]

  • Animal Models

    Genetically heterogeneous UM-HET3 mice

  • Dosages

    14.4 mg/kg

  • Administration

    p.o.

Selleck's Alpha-Estradiol has been cited by 1 publication

Novel Estrogen Receptor Dimerization BRET-Based Biosensors for Screening Estrogenic Endocrine-Disrupting Chemicals [ Biomater Res, 2024, 28:0010] PubMed: 38464469

RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.

SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.