Oleanolic Acid

Catalog No.S2334 Batch:S233403

Technical Data

Formula

C₃₀H₄₈O₃

Molecular Weight

456.7

CAS No.

508-02-1

Solubility (25°C)*

In vitro

DMSO (warmed with 50ºC water bath)

25 mg/mL (54.74 mM)

Ethanol

2 mg/mL (4.37 mM)

Water

Insoluble

In vivo (Add solvents to the product individually and in order)

Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
Clear solution	5%DMSO 1 40%PEG300 2 5%Tween80 3 50%ddH2O Validated by Selleck labs. Should you need adjustments to this formulation, contact our sales team for custom testing.	1.25mg/ml (2.74mM)	Taking the 1 mL working solution as an example, add 50 μL of 25 mg/ml clarified DMSO stock solution to 400 μL of PEG300, mix evenly to clarify it; add 50 μL of Tween80 to the above system, mix evenly to clarify; then continue to add 500 μL of ddH2O to adjust the volume to 1 mL. The mixed solution should be used immediately for optimal results.
Clear solution	5% DMSO 1 95% Corn oil Validated by Selleck labs. Should you need adjustments to this formulation, contact our sales team for custom testing.	0.175mg/ml (0.38mM)	Taking the 1 mL working solution as an example, add 50 μL of 3.5 mg/ml clear DMSO stock solution to 950 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results.

* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description	Oleanolic Acid (Caryophyllin) is a non-toxic, hepatoprotective triterpenoid found in Phytolacca Americana, which exerts antitumor and antiviral properties.
In vitro	Oleanolic Acid is a non-toxic, hepatoprotective triterpenoid found in Phytolacca Americana which exerts antitumor and antiviral properties. Oleanolic acid is effective in protecting against chemically induced liver injury in laboratory animals. Oleanolic acid are relatively non-toxic, and has been used in cosmetics and health products. ^[1] Oleanolic acid was found to exhibit weak anti-HIV and weak anti-HCV activities, but more potent synthetic analogs are being investigated as potential drugs. ^[2]

Description

Oleanolic Acid (Caryophyllin) is a non-toxic, hepatoprotective triterpenoid found in Phytolacca Americana, which exerts antitumor and antiviral properties.

In vitro

Oleanolic Acid is a non-toxic, hepatoprotective triterpenoid found in Phytolacca Americana which exerts antitumor and antiviral properties. Oleanolic acid is effective in protecting against chemically induced liver injury in laboratory animals. Oleanolic acid are relatively non-toxic, and has been used in cosmetics and health products. ^[1] Oleanolic acid was found to exhibit weak anti-HIV and weak anti-HCV activities, but more potent synthetic analogs are being investigated as potential drugs. ^[2]

Protocol (from reference)

References

Selleck's Oleanolic Acid has been cited by 5 publications

Oleanolic acid improves 5-fluorouracil-induced intestinal damage and inflammation by alleviating intestinal senescence [ Sci Rep, 2024, 14(1):21852]	PubMed: 39300121
Oleanolic Acid Improves Obesity-Related Inflammation and Insulin Resistance by Regulating Macrophages Activation [ Front Pharmacol, 2021, 12:697483]	PubMed: 34393781
AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer [ J Cell Sci, 2021, 134(8)jcs255273]	PubMed: 33758077
3α,19-Dihydroxyl-ent-pimara-8(14),15-diene, a new diterpenoid from the rhizomes of Ricinus communis [ J Asian Nat Prod Res, 2019, 21(6):522-527]	PubMed: 29665732
3α,19-Dihydroxyl-ent-pimara-8(14),15-diene, a new diterpenoid from the rhizomes of Ricinus communis [Sheng-Nan Zhang, et al. J Asian Nat Prod Res, 2018, 10.1080/10286020.2018.1461087]

RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.