Bisoprolol fumarate

Catalog No.S1206 Batch:S120601

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Technical Data

Formula

C22H35NO8

Molecular Weight 441.52 CAS No. 104344-23-2
Solubility (25°C)* In vitro DMSO 88 mg/mL (199.31 mM)
Water 88 mg/mL (199.31 mM)
Ethanol 88 mg/mL (199.31 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

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Biological Activity

Description Bisoprolol fumarate (EMD33512) is a selective type β1 adrenergic receptor blocker.
Targets
β1-adrenergic receptor [1]

Protocol (from reference)

Selleck's Bisoprolol fumarate has been cited by 6 publications

Targeting the β2 -adrenergic receptor increases chemosensitivity in multiple myeloma by induction of apoptosis and modulating cancer cell metabolism [ J Pathol, 2022, 10.1002/path.6020] PubMed: 36245401
The Influence of EGCG on the Pharmacokinetics and Pharmacodynamics of Bisoprolol and a New Method for Simultaneous Determination of EGCG and Bisoprolol in Rat Plasma [ Front Nutr, 2022, 9:907986] PubMed: 35711541
Gentisic acid prevents the transition from pressure overload-induced cardiac hypertrophy to heart failure. [ Sci Rep, 2019, 9(1):3018] PubMed: 30816171
High-throughput quantification of ten antiarrhythmic drugs in human plasma using UPLC-MS/MS. [ J Chromatogr B Analyt Technol Biomed Life Sci, 2019, 1129:121793] PubMed: 31629310
Gentisic acid attenuates pressure overload-induced cardiac hypertrophy and fibrosis in mice through inhibition of the ERK1/2 pathway [Sun S, et al. J Cell Mol Med, 2018, 22(12):5964-5977] PubMed: 30256522
Evaluation system for arrhythmogenic potential of drugs using human-induced pluripotent stem cell-derived cardiomyocytes and gene expression analysis [Higa A, et al. J Toxicol Sci, 2017, 42(6):755-761] PubMed: 29142174

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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.