Asiatic Acid

Catalog No.S2266 Batch:S226602

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Technical Data

Formula

C30H48O5

Molecular Weight 488.70 CAS No. 464-92-6
Solubility (25°C)* In vitro DMSO 98 mg/mL (200.53 mM)
Ethanol 15 mg/mL (30.69 mM)
Water Insoluble
In vivo (Add solvents to the product individually and in order)
Homogeneous suspension
CMC-NA
≥5mg/ml Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Asiatic acid (Dammarolic acid, Asiantic acid) is the aglycone of asiaticoside isolated from the plant Centella asiatica, commonly used in wound healing.
Targets
p38 MAPK [1]

Protocol (from reference)

References

  • https://pubmed.ncbi.nlm.nih.gov/15626723/

Selleck's Asiatic Acid Has Been Cited by 21 Publications

In Silico Analyses and Cytotoxicity Study of Asiaticoside and Asiatic Acid from Malaysian Plant as Potential mTOR Inhibitors [ Molecules, September 02, 2020, 3991] PubMed: nan
In Silico Analyses and Cytotoxicity Study of Asiaticoside and Asiatic Acid from Malaysian Plant as Potential mTOR Inhibitors [ Molecules, September 02 2020, 3991]
Dioscin Inhibits the Invasion and Migration of Hepatocellular Carcinoma HepG2 Cells by Reversing TGF-β1-Induced Epithelial-Mesenchymal Transition [ Molecules, June 14, 2019, 2222] PubMed: 31197076
Ras-Responsive Element Binding Protein 1 regulates survival of Group 3 medulloblastoma [ bioRxiv, July 21, 2025, 2025.07.16.665230] PubMed: 40777316
Asiatic Acid Attenuates Osteoporotic Bone Loss in Ovariectomized Mice Through Inhibiting NF-kappaB/MAPK/ Protein Kinase B Signaling Pathway [ Frontiers in Pharmacology, February 08, 2022, 829741] PubMed: 35211021
Asiatic Acid Attenuates Osteoporotic Bone Loss in Ovariectomized Mice Through Inhibiting NF-kappaB/MAPK/ Protein Kinase B Signaling Pathway [ Frontiers in Pharmacology, February 08 2022, 829741] PubMed: 35211021
Nuciferine induces autophagy to relieve vascular cell adhesion molecule 1 activation via repressing the Akt/mTOR/AP1 signal pathway in the vascular endothelium [ Front Pharmacol, 2023, 14:1264324] PubMed: 37841916
Nuciferine induces autophagy to relieve vascular cell adhesion molecule 1 activation via repressing the Akt/mTOR/AP1 signal pathway in the vascular endothelium [ Frontiers in Pharmacology, 2023, 1264324] PubMed: 37841916
Graphene oxide/gallium nanoderivative as a multifunctional modulator of osteoblastogenesis and osteoclastogenesis for the synergistic therapy of implant-related bone infection [ Bioactive Materials, 2022, 594-614] PubMed: 37056253
Maternal consumption of a fermented diet protects offspring against intestinal inflammation by regulating the gut microbiota [ Gut Microbes, 2022, 14(1):2057779] PubMed: 35506256

RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.

SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.