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Technical Data
| Formula | C20H30O5 |
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| Molecular Weight | 350.45 | CAS No. | 5508-58-7 | |
| Solubility (25°C)* | In vitro | DMSO | 70 mg/mL (199.74 mM) | |
| Water | Insoluble | |||
| Ethanol | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Andrographolide is a labdane diterpenoid that is the main bioactive component of the medicinal plant Andrographis paniculata. | |
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Protocol (from reference)
Selleck's Andrographolide has been cited by 10 publications
| Andrographolide Inhibits Corneal Fibroblast to Myofibroblast DifferentiationIn Vitro [ Biomolecules, 2022, 12(10), 1447] | PubMed: None |
| Andrographolide Inhibits Corneal Fibroblast to Myofibroblast Differentiation In Vitro [ Biomolecules, 2022, 12-101447] | PubMed: 36291655 |
| Andrographolide Inhibits ER-Positive Breast Cancer Growth and Enhances Fulvestrant Efficacy via ROS-FOXM1-ER-α Axis [ Front Oncol, 2022, 12:899402] | PubMed: 35615146 |
| Endothelial Cell-Derived SO2 Controls Endothelial Cell Inflammation, Smooth Muscle Cell Proliferation, and Collagen Synthesis to Inhibit Hypoxic Pulmonary Vascular Remodelling [ Oxid Med Cell Longev, 2021, 2021:5577634] | PubMed: 33953829 |
| Andrographolide Induces Apoptosis in Human Osteosarcoma Cells via the ROS/JNK Pathway [ Int J Oncol, 2020, 56(6):1417-1428] | PubMed: 32236589 |
| In vitro benchmarking of NF-κB inhibitors. [ Eur J Pharmacol, 2020, 873:172981] | PubMed: 32014486 |
| Visualization of GLUT1 Trafficking in Live Cancer Cells by the Use of a Dual-Fluorescence Reporter [ ACS Omega, 2020, 5(26):15911-15921] | PubMed: 32656411 |
| An antiviral drug screening system for enterovirus 71 based on an improved plaque assay: A potential high-throughput method [ J Med Virol, 2019, 91(8):1440-1447] | PubMed: 30900754 |
| Andrographolide inhibits inflammatory responses in LPS-stimulated macrophages and murine acute colitis through activating AMPK. [ Biochem Pharmacol, 2019, 170:113646] | PubMed: 31545974 |
| Natural molecules induce and synergize to boost expression of the human antimicrobial peptide β-defensin-3. [ Proc Natl Acad Sci U S A, 2018, 115(42):E9869-E9878] | PubMed: 30275324 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.