:root {
    --navy: #0a2a5d;
    --navy-600: #153e75;
    --blue: #1e5aa6;
    --gold: #bf9b30;
    --gold-600: #a6852a;
    --ink: #222;
    --muted: #6b7280;
    --line: #e6e8ef;
    --soft: #f5f7fb;
    --hover: #f2f8ff;
    --white: #fff;
}
#bio-widget-animal, #bio-widget-cell {font-family: "Segoe UI", Roboto, Helvetica, Arial, sans-serif;font-size: 13px; color: #333; line-height: 1.4;border: 1px solid #ddd; border-radius: 4px; background: #fff;box-shadow: 0 2px 5px rgba(0,0,0,0.05); overflow: hidden;display: flex; flex-direction: column;}
#bio-widget-animal .bio-step-title, #bio-widget-cell .bio-step-title {padding: 12px 15px; font-size: 14px; font-weight: 700;background: #f8f9fa; border-bottom: 1px solid #ddd;margin: 0; flex-shrink: 0;}
#bio-widget-animal .bio-tabs-header, #bio-widget-cell .bio-tabs-header {background: #f8f9fa8c; border-bottom: 1px solid #ddd; padding: 8px 12px;display: flex; flex-wrap: wrap; gap: 8px; flex-shrink: 0;}
#bio-widget-animal .bio-tab, #bio-widget-cell .bio-tab {padding: 4px 12px; font-weight: 600; color: #555; cursor: pointer;border: 1px solid #ddd; border-radius: 15px; background: #fff;transition: all 0.2s; display: inline-flex; align-items: center; gap: 6px;font-size: 12px; user-select: none;}
#bio-widget-animal .bio-tab:hover, #bio-widget-cell .bio-tab:hover { border-color: #999; color: #000; }
#bio-widget-animal .bio-tab.active, #bio-widget-cell .bio-tab.active {background: #007bff; color: #fff; border-color: #007bff;}
#bio-widget-animal .bio-tab-count, #bio-widget-cell .bio-tab-count {background: rgba(0,0,0,0.1); color: inherit; border-radius: 10px; padding: 0 5px; font-size: 10px;}
#bio-widget-animal .bio-subtabs-header, #bio-widget-cell .bio-subtabs-header {background: #fff; border-bottom: 1px solid #eee; padding: 8px 15px;display: flex; flex-wrap: wrap; gap: 8px;display: none; flex-shrink: 0; align-items: center;}
#bio-widget-animal .bio-subtab, #bio-widget-cell .bio-subtab {padding: 3px 10px; font-weight: 500; color: #555; cursor: pointer;border: 1px solid #ddd; border-radius: 12px; background: #f9f9f9;transition: all 0.2s; font-size: 12px; user-select: none;}
#bio-widget-animal .bio-subtab:hover, #bio-widget-cell .bio-subtab:hover { border-color: #007bff; color: #007bff; }
#bio-widget-animal .bio-subtab.active, #bio-widget-cell .bio-subtab.active {background: #007bff; color: #fff; border-color: #007bff;}
#bio-widget-animal .bio-search-wrapper, #bio-widget-cell .bio-search-wrapper {flex: none; display: flex; gap: 0; align-items: center;margin-left: 8px;}
#bio-widget-animal .bio-search-input, #bio-widget-cell .bio-search-input, .table-filter-container .cs-table-search-input {width: 150px;padding: 5px 8px; border: 1px solid #ddd;border-radius: 3px; font-size: 13px;}
#bio-widget-animal .bio-btn, #bio-widget-cell .bio-btn {padding: 7px 12px; background: #f8f9fa; border: 1px solid #ddd;border-top-right-radius: 3px; border-bottom-right-radius: 3px;cursor: pointer; color: #333; font-weight: 600; font-size: 12px;}
#bio-widget-animal .bio-btn:hover, #bio-widget-cell .bio-btn:hover { background-color: #e9ecef; }
#bio-widget-animal .bio-content-area, #bio-widget-cell .bio-content-area {background: #fff; border-bottom: 1px solid #eee;display: none; flex-grow: 1;overflow-y: auto; max-height: 600px; padding: 10px 15px;}
#bio-widget-animal .bio-content-area::-webkit-scrollbar, #bio-widget-cell .bio-content-area::-webkit-scrollbar { width: 6px; }
#bio-widget-animal .bio-content-area::-webkit-scrollbar-thumb, #bio-widget-cell .bio-content-area::-webkit-scrollbar-thumb { background: #ccc; border-radius: 3px; }
#bio-widget-animal .bio-badges, #bio-widget-cell .bio-badges { display: flex; gap: 5px; font-size: 10px; margin-bottom: 10px; }
#bio-widget-animal .bio-badge, #bio-widget-cell .bio-badge { padding: 1px 5px; border-radius: 3px; background: #e7f5ff; color: #007bff; border: 1px solid #d0ebff; }
#bio-widget-animal .bio-badge.high, #bio-widget-cell .bio-badge.high { background: #fff9db; color: #e67700; border-color: #ffec99; }
#bio-widget-animal .bio-detail-sort-bar, #bio-widget-cell .bio-detail-sort-bar {display: flex; justify-content: flex-start;gap: 5px; margin-bottom: 8px; font-size: 11px; color: #666; align-items: center;}
#bio-widget-animal .bio-mini-btn, #bio-widget-cell .bio-mini-btn {border: 1px solid #ced4da; background: #fff; padding: 1px 6px; border-radius: 3px; cursor: pointer; color: #555;display: flex; align-items: center; gap: 3px;}
#bio-widget-animal .bio-mini-btn.active, #bio-widget-cell .bio-mini-btn.active {background: #007bff; color: #fff; border-color: #007bff;}
#bio-widget-animal .bio-sort-arrow, #bio-widget-cell .bio-sort-arrow { font-size: 9px; }
/*#bio-widget-animal .bio-card, #bio-widget-cell .bio-card {background: #fff; border: 1px solid #ddd; border-left: 3px solid #28a745;border-radius: 4px; padding: 8px 170px 8px 10px;margin-bottom: 6px; position: relative; box-shadow: 0 1px 2px rgba(0,0,0,0.02);}*/
/*#bio-widget-animal .bio-card-meta, #bio-widget-cell .bio-card-meta {display: flex; flex-wrap: wrap; gap: 6px; margin-bottom: 4px; align-items: center;}*/
#bio-widget-animal .bio-tag, #bio-widget-cell .bio-tag {font-size: 10px; padding: 0 5px; border-radius: 3px; border: 1px solid #ddd;background: #f1f3f5; color: #555; height: 18px; line-height: 16px; white-space: nowrap;}
#bio-widget-animal .bio-tag.concentration-tag, #bio-widget-cell .bio-tag.concentration-tag { color: #856404; font-weight: bold; }
#bio-widget-animal .bio-tag.duration-tag, #bio-widget-cell .bio-tag.duration-tag { color: #099268; font-weight: bold; }
#bio-widget-animal .bio-tag.if-tag.active-sort, #bio-widget-cell .bio-tag.if-tag.active-sort {background: #007bff; color: #fff; border-color: #007bff;}
#bio-widget-animal .bio-tag.citation-tag.active-sort, #bio-widget-cell .bio-tag.citation-tag.active-sort {background: #007bff; color: #fff; border-color: #007bff;}
#bio-widget-animal .bio-tag.date-tag.active-sort, #bio-widget-cell .bio-tag.date-tag.active-sort {background: #007bff; color: #fff; border-color: #007bff;}
/*#bio-widget-animal .bio-card-actions, #bio-widget-cell .bio-card-actions {position: absolute; top: 8px; right: 10px;display: flex; align-items: center; gap: 10px;}*/
#bio-widget-animal .bio-download-link, #bio-widget-cell .bio-download-link {font-size: 11px; color: #007bff; text-decoration: none; font-weight: 600;background: #fff; padding: 2px 6px; border: 1px solid #dee2e6; border-radius: 3px;}
#bio-widget-animal .bio-download-link:hover, #bio-widget-cell .bio-download-link:hover { background-color: #f8f9fa; border-color: #007bff; }
#bio-widget-animal .bio-thumb-img, #bio-widget-cell .bio-thumb-img {width: 24px; height: 32px; border: 1px solid #ccc; border-radius: 2px;object-fit: cover; cursor: pointer; transition: transform 0.2s, box-shadow 0.2s;background: #fff;}
#bio-widget-animal .bio-thumb-img:hover, #bio-widget-cell .bio-thumb-img:hover {transform: scale(1.5); box-shadow: 0 2px 5px rgba(0,0,0,0.2); z-index: 10;border-color: #007bff;}
/*#bio-widget-animal .bio-concl, #bio-widget-cell .bio-concl { font-size: 12px; color: #212529; margin-top: 4px; }*/
#bio-widget-animal .bio-sub-model-title, #bio-widget-cell .bio-sub-model-title{font-weight: 700; font-size: 13px; margin: 12px 0 6px 0; color: #007bff;}


.cs-container { width:1346px;margin: 0 auto; padding: 20px 10px 10px 10px; font-family: "Helvetica Neue", Arial, sans-serif; color: #333; line-height: 1.8; }
.cs-hero { background: #fdfdfd; padding: 20px 30px; border-radius: 8px; margin-bottom: 30px; border-left: 6px solid #4a90e2; border-bottom: 1px solid #eee; }
.cs-hero h1 { color: #2c3e50; margin-top: 0; font-size: 26px; line-height: 1.4; }
.cs-hero p { color: #7f8c8d; font-size: 18px; font-weight: normal; margin-top: 20px; line-height: 1.6; }
ul {list-style: none;padding: 0;margin: 0;}
.cs-outline li {margin: 0;position: relative;padding-left: 1.2em;}
.cs-outline li::before {content: "–";position: absolute;left: 0;color: #555;}
.cs-outline {text-decoration: none !important;position: relative;background: none;border: none;}
.cs-container h2 { position: relative;font-size:19px;text-indent: 15px; }
.cs-container h2::before {content: "";height: 15px;background-color: #4a90e2;width: 3px;position: absolute;top: 9px;left: 0;border-radius: 5px;}
.cs-content-body p { margin-bottom: 25px; font-size: 16px; color: #444; text-align: justify; }
#carftSolubilityInvitor p { margin-bottom: 0px; }
.cs-block { background: #f9f9f9; border-top: 1px solid #eee; border-bottom: 1px solid #eee; padding: 30px; margin: 30px 0; }
.cs-table-wrapper { margin: 5px 0 15px 0; overflow-x: auto; }
.cs-table-wrapper .default-hidden-row {display: none;}
.cs-sci-table th,.cs-sci-table2 th { background-color: #f4f7f9; color: #44546a; padding: 10px; font-weight: bold; border: 1px solid #e0e0e0; border-bottom: 2px solid #cfd8dc;text-align:center;line-height: 1.5;font-size: 14px;}
.cs-sci-table td,.cs-sci-table2 td { padding: 12px; border: 1px solid #e0e0e0; text-align: center; color: #555;font-size: 13px; line-height: 1.5;}
.cs-sci-table tr:nth-child(even),.cs-sci-table2 tr:nth-child(even) { background-color: #fafbfc; }
.cs-sci-table tr:hover,.cs-sci-table2 tr:hover { background-color: #f1f7ff; }
.cs-sci-table2 th,.cs-sci-table2 td { text-align:left !important;}
.cs-footer { border-top: 1px solid #eee; font-size: 14px; color: #666;}
.cs-highlight-selleck { color: #c21b3e; font-weight: bold; }
.table-caption { font-size: 13px !important; color: #888 !important; margin-top: 10px; font-style: italic; }
#othersAnimalTable li,#othersAnimalTable2 li{display: inline-block; padding: 0px 10px; border:1px solid #ddd;border-radius:6px;margin-right: 5px;margin-bottom: 5px;}
#othersAnimalTable li:hover,#othersAnimalTable2 li:hover{cursor: pointer;}
#othersAnimalTable li.active,#othersAnimalTable2 li.active{background: #007bff; color: #fff; border-color: #007bff;}

.card { border: 1px solid #ddd; border-radius: 10px; padding: 16px; }
.card input{border:1px solid #ddd;}
button { cursor: pointer; }
button:disabled { opacity: 0.6; cursor: not-allowed; }
pre { margin: 0; white-space: pre-wrap; word-break: break-word; }
.toolbar {display: flex;flex-wrap: wrap;gap: 10px;align-items: center;padding: 5px 12px;background: linear-gradient(180deg, #fbfcff, var(--soft));border: 1px solid var(--line);border-radius: 12px;box-shadow: 0 2px 6px rgba(10, 42, 93, .06);margin: 0 0 10px;}
.toolbar label {font-weight: 700;color: var(--navy)}
.select {position: relative;display: inline-block;}
.select select, .search-box {appearance: none;-webkit-appearance: none;-moz-appearance: none;padding: 8px 36px 8px 10px;border: 1px solid #cbd5e1;border-radius: 10px;background: var(--white);font-size: 14px;color: var(--navy-600);font-weight: 600;transition: border-color .2s ease, box-shadow .2s ease;}
.select select:focus {outline: none;border-color: var(--blue);box-shadow: 0 0 0 4px rgba(30, 90, 166, .15)}
.select .chev {position: absolute;right: 10px;top: 50%;transform: translateY(-50%);pointer-events: none;color: var(--gold);font-size: 14px;}
.loadMore {background: linear-gradient(180deg, #fbfcff, var(--soft));color: var(--navy);border: 1px solid  var(--line);padding: 5px 10px;border-radius: 22px;font-weight: 700;font-size: 14px;}
.nowrap {white-space: nowrap}

/* --- Comparative Analysis --- */
.product-name-link {color: #007bff;text-decoration: none;font-weight: 600;}
.product-name-link:hover {color: #0056b3;text-decoration: underline;}
.bio-card {
    display: grid;grid-template-columns: 1fr auto;grid-template-rows: auto auto auto;gap: 0px 25px;
    background: #fff; border: 1px solid #eee; border-left: 3px solid #28a745;padding: 16px 20px; transition: background 0.1s, border-color 0.1s;margin-bottom: 6px; border-radius: 4px;box-shadow: 0 1px 2px rgba(0,0,0,0.02);}
.bio-card2 {
    display: flex;flex-direction: column;
    background: #fff; border: 1px solid #eee; border-left: 3px solid #28a745;padding: 16px 20px; transition: background 0.1s, border-color 0.1s;margin-bottom: 6px; border-radius: 4px;box-shadow: 0 1px 2px rgba(0,0,0,0.02);}
.bio-card:hover,.bio-card2:hover { background: #fcfdfe; border-left-color: #00838f; }
.bio-card:last-child,.bio-card2:last-child { margin-bottom: 0; }
.bio-card-meta {
    grid-column: 1 / 2; grid-row: 1 / 2;
    display: flex; flex-wrap: wrap; gap: 6px; align-items: center;}
.bio-concl {
    grid-column: 1 / 2; grid-row: 2 / 3;
    display: flex; flex-wrap: wrap; gap: 6px; align-items: center;}
.bio-card-actions {
    grid-column: 2 / 3; grid-row: 1 / 3;
    display: flex;align-items: center;gap: 10px;align-self: center;flex-direction: row-reverse;}
.bio-tag {font-size: 11px; padding: 2px 8px; border-radius: 4px; border: 1px solid #ddd;background: #f1f3f5; color: #555; white-space: nowrap; font-weight: 600;}
.bio-tag.model-name { background: #e7f5ff; color: #0056b3; border-color: #a5d8ff; }
.bio-tag.jcr-tag { background: #fff4e6; color: #e8590c; border-color: #ffd8a8; }
.bio-tag.cas-tag { background: #e3fafc; color: #0b7285; border-color: #99e9f2; }
.bio-tag.target-tag { background: #e0f7fa; color: #00838f; border-color: #b2ebf2; }
.bio-download-link,#cc-widget-multiple .pw-download-link {font-size: 11px; color: #007bff; text-decoration: none; font-weight: 600;background: #fff; padding: 4px 8px; border: 1px solid #dee2e6; border-radius: 3px;display: inline-block; white-space: nowrap; transition: 0.2s;margin-top: 4px;}
.bio-download-link:hover,#cc-widget-multiple .pw-download-link:hover { background-color: #f8f9fa; border-color: #007bff; }
.bio-img-container {display: flex;flex-direction: column;align-items: center;gap: 4px;}
.bio-img-container2 {display: flex;flex-direction: row;align-items: center;gap: 4px;}
.bio-thumb-img {width: 30px; height: 40px; border: 1px solid #ccc; border-radius: 2px;object-fit: cover; cursor: pointer; transition: transform 0.2s, box-shadow 0.2s;background: #fff;}
.bio-thumb-img:hover {transform: scale(1.6); box-shadow: 0 4px 8px rgba(0,0,0,0.2); z-index: 10;border-color: #007bff;}
.bio-img-caption {font-size: 9px;color: #6c757d;white-space: nowrap;text-align: center;}
/* --- combination compounds --- */
#cc-widget-multiple {font-family: "Segoe UI", Roboto, Helvetica, Arial, sans-serif;font-size: 13px; color: #333; line-height: 1.4;border: 1px solid #ddd; border-radius: 4px; background: #fff;box-shadow: 0 2px 5px rgba(0,0,0,0.05); overflow: hidden;}
#cc-widget-multiple .pw-header-title {background: #f8f9fa;padding: 15px 15px 10px;font-size: 18px;font-weight: 600;color: #333;border-bottom: 1px solid #eee;}
#cc-widget-multiple .pw-tabs-header {background: #f8f9fa;border-bottom: 1px solid #ddd;padding: 10px 15px 15px;display: flex; flex-wrap: wrap; gap: 8px; align-items: center;}
#cc-widget-multiple .pw-tab {padding: 4px 12px; font-weight: 600; color: #555; cursor: pointer;border: 1px solid #ddd; border-radius: 15px; background: #fff;transition: all 0.2s; display: inline-flex; align-items: center; gap: 6px;font-size: 12px; user-select: none;}
#cc-widget-multiple .pw-tab:hover { border-color: #999; color: #000; transform: translateY(-1px); }
#cc-widget-multiple .pw-tab.active {background: #28a745; color: #fff; border-color: #28a745;}
#cc-widget-multiple .pw-tab-count {background: rgba(0,0,0,0.1); color: inherit; border-radius: 10px; padding: 0 5px; font-size: 10px;}
#cc-widget-multiple .pw-sub-tabs {padding: 8px 15px; background: #fff; border-bottom: 1px solid #eee;display: flex; gap: 8px; flex-wrap: wrap;}
#cc-widget-multiple .pw-sub-tab {padding: 5px 14px; border: 1px solid #ddd; border-radius: 4px;cursor: pointer; font-size: 13px; font-weight: 500; background: #f8f9fa;transition: all 0.2s;}
#cc-widget-multiple .pw-sub-tab.active {background: #007bff; color: #fff; border-color: #007bff;}
#cc-widget-multiple .pw-sub-tab:hover { border-color: #007bff; }
#cc-widget-multiple .pw-data-sort-bar {padding: 8px 15px; display: flex; align-items: center; gap: 8px;font-size: 12px; color: #666; border-bottom: 1px solid #eee;}
#cc-widget-multiple .pw-mini-btn {padding: 5px 14px; border: 1px solid #ddd; border-radius: 4px;cursor: pointer; font-size: 13px; font-weight: 500; background: #f8f9fa;transition: all 0.2s; display: inline-flex; align-items: center; gap: 3px;}
#cc-widget-multiple .pw-mini-btn.active {background: #007bff; color: #fff; border-color: #007bff;}
#cc-widget-multiple .pw-mini-btn:hover { border-color: #007bff; }
#cc-widget-multiple .pw-content-area {max-height: 680px; overflow-y: auto; background: #fff;padding: 0 15px 10px 15px;}
#cc-widget-multiple .pw-card {background: #fff; border: 1px solid #ddd; border-left: 3px solid #28a745;border-radius: 6px; padding: 12px 90px 12px 15px;margin-bottom: 8px; position: relative; box-shadow: 0 1px 3px rgba(0,0,0,0.04);transition: transform 0.2s, border-left-color 0.2s;}
#cc-widget-multiple .pw-card:hover { border-left-color: #00838f; }
#cc-widget-multiple .pw-card-meta {display: flex; flex-wrap: wrap; gap: 6px; margin-bottom: 8px; align-items: center;}
#cc-widget-multiple .pw-tag {font-size: 11px; padding: 2px 6px; border-radius: 4px; border: 1px solid #ddd;background: #f1f3f5; color: #555; white-space: nowrap; font-family: "Segoe UI", sans-serif;}
#cc-widget-multiple .pw-tag.highlight-sort {background: #007bff;color: #fff;border-color: #007bff;font-weight: 600;}
#cc-widget-multiple .pw-tag.model-name.selected-compound {background: #28a745;color: #fff;border-color: #28a745;font-weight: 600;}
#cc-widget-multiple .pw-card-actions {position: absolute; top: 7px; right: 15px;}
#cc-widget-multiple .pw-concl { font-size: 13px; color: #212529; margin-top: 4px; line-height: 1.5; font-weight: 500; }
#cc-widget-multiple .pw-protocol-box {background: #f8f9fa; border: 1px solid #e9ecef; border-radius: 6px;padding: 12px 15px; margin-top: 12px; position: relative;}
#cc-widget-multiple .pw-protocol-label {position: absolute; top: -9px; left: 12px; background: #fff; padding: 0 6px;font-size: 11px; color: #999; font-weight: 600; border: 1px solid #e9ecef; border-radius: 4px;}
#cc-widget-multiple .pw-protocol-text {font-family: Consolas, monospace; font-size: 12px; color: #444; white-space: pre-wrap; margin-top: 4px;}

.img-modal {display: none; position: fixed; z-index: 9999;left: 0; top: 0; width: 100vw; height: 100vh; background-color: rgba(0, 0, 0, 0.85);}
.img-modal-content {position: absolute; top: 50%; left: 50%; transform: translate(-50%, -50%);max-width: 90vw; max-height: 90vh; border-radius: 8px; box-shadow: 0 4px 20px rgba(0,0,0,0.5);object-fit: contain; animation: zoomInCenter 0.3s forwards;}
@keyframes zoomInCenter {
    from { transform: translate(-50%, -50%) scale(0.8); opacity: 0; }
    to { transform: translate(-50%, -50%) scale(1); opacity: 1; }
}
.img-modal-close {position: absolute; top: 20px; right: 40px; color: #fff; font-size: 40px; font-weight: bold;transition: 0.3s; cursor: pointer; z-index: 10000;}
.img-modal-close:hover { color: #bbb; text-decoration: none; }