p70 S6K Selective Inhibitors

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S7698 LY2584702

LY2584702 is a selective, ATP-competitive p70S6K inhibitor with IC50 of 4 nM. Phase 1.

Selective p70S6K, IC50: 4 nM
S7704 LY2584702 Tosylate

LY2584702 Tosylate is a selective, ATP-competitive p70S6K inhibitor with IC50 of 4 nM. Phase 1.

Selective p70S6K, IC50: 4 nM
S7563 AT13148

AT13148 is an oral, ATP-competitive, multi-AGC kinase inhibitor with IC50 of 38 nM/402 nM/50 nM, 8 nM, 3 nM, and 6 nM/4 nM for Akt1/2/3, p70S6K, PKA, and ROCKI/II, respectively. Phase 1.

Selective p70S6K, IC50: 8 nM
S1558 AT7867

AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively; little activity outside the AGC kinase family.

Pan p70 S6K, IC50: 85 nM