• Carbonic Anhydrase I
  • Carbonic Anhydrase II
  • Carbonic Anhydrase IV
  • Carbonic Anhydrase IX
  • Carbonic Anhydrase XII

Carbonic Anhydrase IV Inhibitors

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S1375 Dorzolamide HCl Dorzolamide (MK-507, L-671152) HCl is a water-soluble, potent inhibitor of human carbonic anhydrase II and IV with Ki of 1.9 nM and 31 nM, respectively, used as anti-glaucoma agent. Pan Carbonic anhydrase IV, Ki: 31 nM
S4039 Methazolamide Methazolamide (CL 8490) is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively. Pan bCAIV, Ki: 36 nM