+ Product Pathways
- All Targets
- Angiogenesis/Tyrosine Kinase
- Cell Cycle/Checkpoint
- HDAC
- Apoptosis
- PARP
- Aurora/Ksp
- MAPK
- PI3K/Akt/mTOR
- Hormone
- Integrase/CCR5
- Proteases/HSP90/HSP70
- Wnt/Hedgehog/Notch
- Jak/Stat
- Ca/cAMP/Lipid Signaling
- Neuro Signaling
- TGF-beta/Smad Signaling
- GPCR
- Ion channel
- Cytochrome P450
- Others
- Cancer
- Infection
- Endocrinology
- Metabolic Disease
- Inflammation
- Immunology
- Neurological Disease
- Cardiovascular Disease
Frequently Asked Questions
Q:Why the compound is not insoluble at the concentration mentioned in the product specification?
A:The solubility data (on the specification) for most of our compounds are directly obtained from the experiment conducted by our R&D and some of them are based on the published figures. If the compound is insoluble in prescribed concentration, it might have been caused by its moisture absorption during the storage. We suggest you warm it up properly and do several minutes’ ultrasonic treatment.
Q:What is the suggested storage condition?
A:Our compounds should be kept at -20℃ in the form of powder to ensure their stablity. If stored in the form of stock solution as aliquots in sealed vials, it should be kept at -20℃. Stock solution could be diluted in cell culture medium, PBS and other solvent, and it should be used within 24 hours once diluted.
Q:Why the results of reduplicate experiments at different times are obviously different?
A:Reasons may be:
(1) Mistake made in preparation and dilution.
(2) Some compounds are not stable in DMSO or other solvent, even if the solution is stored at low temperature. So you have to make it up again with the powder left.
*For further information or support contact Selleck directly by tech@selleckchem.com(chemistry support) and techbio@selleckchem.com(bio support).
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Customer's Feedback
| Dongfeng Chen, The Rausing Lab |
| "Your product U0126(Cat.NO S1102) works well in our experiments. I hope I can get more excellent products from your company in future." |
| R.B. Cambridge |
| "I have used the chemical that I bought from you(Selleck,PTC-124) and it worked well.So we will eventually be ordering more." |
| Zhenghe John Wang Assistant Professor, Case Western Reserve University |
| "We have purchased LBH-589, Saha and MS-275 from you and they all worked well." |
| Jenny Sun |
| "We used the LBH-589 in our experiments. The compound is easy to use with excellent reproducibility." |
| Yu Wang, Harvard University |
| "The GDC0449 compound worked very well. The results in my hands are equally good as what's been published. Thanks for this great resource for our research." |
| Dung-Fang Lee |
| "Based on our preliminary data, I found MLN8237 and VX-680 have good effects in inhibiting Aurka-maintaining ESC self-renewal in mouse ES cells." |
Latest Catalog
| May 2010 Selleck Latest Catalog |  |
