i-Inositol

Synonyms: myo-inositol

i-Inositol, also known as myo-inositol, is a chemical compound which is sugar alcohol. i-Inositol is involved in a number of biological processes including insulin signal transduction, cytoskeleton transduction and so on.

i-Inositol Chemical Structure

i-Inositol Chemical Structure

CAS: 87-89-8

Purity & Quality Control

Batch: Purity: >97%
97

i-Inositol Related Products

Biological Activity

Description i-Inositol, also known as myo-inositol, is a chemical compound which is sugar alcohol. i-Inositol is involved in a number of biological processes including insulin signal transduction, cytoskeleton transduction and so on.
In vitro
In vitro In vitro, Myo-Inositol is able to improve the sperm mitochondrial function in patients with altered sperm parameters[3].
In Vivo
In vivo Myo-Inositol (MI) is one of the most abundant metabolites in the human brain located mainly in glial cells and functions as an osmolyte. its concentration is altered in many brain disorders. MI is a key precursor of membrane phospho-inositides and phospholipids and it is also involved in cell membrane and myelin sheet structures[1]. The addition of myo-inositol to folic acid in non PCOS-patients undergoing multiple follicular stimulation for in-vitro fertilization may reduce the numbers of mature oocytes and the dosage of rFSH whilst maintaining clinical pregnancy rate[2].
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT02811133 Withdrawn
Bipolar Disorder|Anxiety Disorders|Anxiety
Ronald M. Glick MD|The Fine Foundation|Jarrow Formulas Inc|University of Pittsburgh
August 2023 Phase 1|Phase 2
NCT05777863 Recruiting
Life Style|Risk Reduction|Cognitive Decline|Aging
Donders Centre for Cognitive Neuroimaging|Wageningen University and Research
May 10 2022 Not Applicable
NCT05497414 Recruiting
Major Depression
Boston University Charles River Campus|One Mind|Brain & Behavior Research Foundation|1907 Foundation
January 31 2022 Not Applicable
NCT05098587 Recruiting
Spinal Cord Injuries|Neuropathic Pain
Swiss Paraplegic Research Nottwil|Haute Ecole de Santé Vaud
August 30 2021 --
NCT05410314 Completed
Lymphoma Hodgkin|Menstrual Irregularity|Fertility Disorders
University of Bari Aldo Moro
February 7 2020 --

Chemical Information & Solubility

Molecular Weight 180.16 Formula

C6H12O6

CAS No. 87-89-8 SDF Download i-Inositol SDF
Smiles C1(C(C(C(C(C1O)O)O)O)O)O
Storage (From the date of receipt)

In vitro
Batch:

Water : 36 mg/mL

DMSO : 6 mg/mL ( (33.3 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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